دورية أكاديمية
Febre maculosa: isolamento de Rickettsia em amostra de biópsia de pele Spotted fever: Rickettsia isolation in skin biopsy sample
| العنوان: | Febre maculosa: isolamento de Rickettsia em amostra de biópsia de pele Spotted fever: Rickettsia isolation in skin biopsy sample |
|---|---|
| المؤلفون: | Heloisa Helana B. Melles, Silvia Colombo, Marcos Vinícius da Silva |
| المصدر: | Revista do Instituto de Medicina Tropical de São Paulo, Vol 34, Iss 1, Pp 37-41 (1992) |
| بيانات النشر: | Universidade de São Paulo |
| سنة النشر: | 1992 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Febre Maculosa, Rickettsia rickettsii, Rickettsiose-sorologia, Rickettsiose-cultivo, Arctic medicine. Tropical medicine, RC955-962 |
| الوصف: | Presença de Rickettsia na pele de doente de Febre Maculosa foi evidenciada por inoculação intraperitoneal em cobaio. O diagnóstico sorológico por imunoflüorescência indireta revelou diferença de título de anticorpos específicos para Rickettsia rickettsii, de 4 vezes entre a 1º e a 3º amostra. Imunoglobulina M (IgM) específica foi detectada nas amostras de sangue, evidência de infecção em atividade ou recente. Foi também detectada a presença de anticorpos específicos para R. rickettsii no soro dos cobaios inoculados. A 2 years old child living in an area of the State of São Paulo, known in the past as endemic for rickettsiosis developed clinical evidences of spotted fever after a tick bite. Rickettsiae were isolated from guinea pigs inoculated with a skin homogenate. In sera tested by indirect immunofluorescence with Rickettsia rickettsii standard antigen, IgG specific antibody titers raised from 1:512 in the first sample to 1:2048 in the third one; IgM specific antibody titer was 1:128 in the three samples. Also positive were sera obtained from the inoculated guinea pigs. In the last 20 years no other case of rickettsial spotted fever has been confirmed by isolation of the agent in Brasil. To our knowlwdge, there are no previous reports of isolation of Rickettsiae through inoculation of skin biopsy homogenates. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English Portuguese |
| تدمد: | 0036-4665 1678-9946 |
| العلاقة: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651992000100007Test; https://doaj.org/toc/0036-4665Test; https://doaj.org/toc/1678-9946Test; https://doaj.org/article/e4dc943a1bba4a9f9d79b82f6f1f8ea4Test |
| DOI: | 10.1590/S0036-46651992000100007 |
| الإتاحة: | https://doi.org/10.1590/S0036-46651992000100007Test https://doaj.org/article/e4dc943a1bba4a9f9d79b82f6f1f8ea4Test |
| رقم الانضمام: | edsbas.926BF247 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 00364665 16789946 |
|---|---|
| DOI: | 10.1590/S0036-46651992000100007 |