التفاصيل البيبلوغرافية
| العنوان: |
Chronic granulomatous disease presenting with invasive aspergillosis and hypogammaglobulinemia. |
| العنوان البديل: |
İnvaziv aspergilloz infeksiyonu ve hipogamaglobulinemi ile başvuran kronik granülomatözlü bir olgu. (Turkish) |
| المؤلفون: |
Keleş, Sevgi, Soysal, Ahmet, Özdemir, Cevdet, Eifan, Aarif O., Bahçeciler, Nerin, Bakir, Mustafa, Barlan, Işıl |
| المصدر: |
Asthma Allergy Immunology / Astim Allerji Immunoloji; Dec2009, Vol. 7 Issue 3, p189-193, 5p, 3 Black and White Photographs, 1 Chart, 1 Graph |
| مصطلحات موضوعية: |
CHRONIC granulomatous disease, IMMUNOLOGICAL deficiency syndromes in children, MYCOSES, LEUCOCYTES, ASPERGILLOSIS, AGAMMAGLOBULINEMIA, PATHOGENIC microorganisms, IMMUNOGLOBULINS, MORTALITY |
| الملخص (بالإنجليزية): |
Chronic granulomatous disease (CGD) is a rare disorder with the unifying characteristics of severe predisposition to bacterial and fungal infections, impaired ability of phagocytic leukocytes to produce microbicidal oxygen metabolites and failure of these cells to kill certain microorganisms. Aspergillus spp. are the most common fungal pathogens in these patients. Cranial aspergillosis is a rare presentation with a high mortality rate. Immunoglobulin levels of CGD patients are usually normal or elevated. We herein describe a five-year-old boy with CGD presenting with disseminated aspergillosis and hypogammaglobulinemia (low IgA and IgG). [ABSTRACT FROM AUTHOR] |
| Abstract (Turkish): |
Kronik granülomatöz hastalık lökositlerin bakteri ve mantarları öldürmesinde önemli rolü olan mikrobisit oksijen metabolitlerini üretme yeteneklerinin bozulması sonucu ortaya çıkan, bakteriyel ve mantar infeksiyonlarına yatkınlık oluşturan klinik bir sendromdur. Aspergillus spp. bu hastalarda en sık karşılaşılan mantar infeksiyonu etkenidir. Kraniyal aspergillozis ise nadiren görülür ve mortalitesi yüksektir. Kronik granülomatözlü hastalarda immünglobulin düzeyleri ise genellikle normal veya yüksektir. Burada, dissemine aspergillozu olup, hipogamaglobulinemi ile seyreden beş yaşında erkek olgu sunulmaktadır. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
