دورية أكاديمية

Accuracy and Reproducibility of Injections from Prefilled “Code Cart” Syringes Compared to Standard Polypropylene Syringes

التفاصيل البيبلوغرافية
العنوان: Accuracy and Reproducibility of Injections from Prefilled “Code Cart” Syringes Compared to Standard Polypropylene Syringes
المؤلفون: Kim, Yoona
المساهمون: Edwards, Christopher J., Nix, David E., Erstad, Brian L., College of Pharmacy, The University of Arizona
بيانات النشر: The University of Arizona.
سنة النشر: 2023
المجموعة: The University of Arizona: UA Campus Repository
مصطلحات موضوعية: accuracy, small-volume injections, prefilled syringes, polypropylene, comparison
الوصف: Class of 2023 Abstract and Poster ; Specific Aims: To evaluate the accuracy and reproducibility of small-volume injections from prefilled syringes and different sizes of polypropylene syringes. Methods: Atropine and epinephrine prefilled syringes were used to measure volumes of 0.5 mL and 1 mL of drug solution. Different sized polypropylene syringes (1-mL, 3-mL, and 10-mL) were used to measure volumes of 0.4 mL and 1 mL drawn from prefilled syringes. The measured volumes were compared to expected delivery volume. For analysis, t-tests and folded F test were conducted for prefilled syringe data and the general linear model and Levene’s test were used for polypropylene syringe data. Results: Both prefilled syringes demonstrated high variability at the 0.5 mL volume. The coefficient of variance (CV) was 14.3% and 15.0% for atropine and epinephrine for the first delivery and 7.39% and 9.41% for the second delivery. The 10-mL polypropylene syringe overdelivered 0.4 mL doses by 17.1% and 10.6% for atropine and epinephrine, respectively. With the 1 mL volume, the accuracy was improved and the expected delivery range was 0.863 to 1.19 mL (19% error). Use of a 3-mL or 1-mL syringe expectantly resulted in improved accuracy and precision. Conclusions: Using a 10-mL syringe, either prefilled or polypropylene, to measure volumes of 1 mL or less did not result in reproducible delivery of doses at the ±10% error threshold. When preparing doses smaller than the 20% of the total volume of a pre-filled syringe, we recommend using the smallest available polypropylene syringe that will accommodate the volume needed. ; This item is part of the Pharmacy Student Research Projects collection, made available by the College of Pharmacy and the University Libraries at the University of Arizona. For more information about items in this collection, please contact Jennifer Martin, Librarian and Clinical Instructor, Pharmacy Practice and Science, jenmartin@email.arizona.edu.
نوع الوثيقة: text
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اللغة: English
العلاقة: http://hdl.handle.net/10150/670910Test
الإتاحة: http://hdl.handle.net/10150/670910Test
حقوق: Copyright © is held by the author. ; http://rightsstatements.org/vocab/InC/1.0Test/
رقم الانضمام: edsbas.97F0D7C0
قاعدة البيانات: BASE