التفاصيل البيبلوغرافية
| العنوان: |
Improving the glial differentiation of human Schwann-like adipose-derived stem cells with graphene oxide substrates |
| المؤلفون: |
Verre, Andrea Francesco, Faroni, Alessandro, Iliut, Maria, Silva, Claudio, Muryn, Cristopher, Reid, Adam J., Vijayaraghavan, Aravind |
| المساهمون: |
Engineering and Physical Sciences Research Council, National Institute for Health Research, Fundação de Amparo à Pesquisa do Estado de São Paulo |
| المصدر: |
Interface Focus ; volume 8, issue 3, page 20180002 ; ISSN 2042-8898 2042-8901 |
| بيانات النشر: |
The Royal Society |
| سنة النشر: |
2018 |
| الوصف: |
There is urgent need to improve the clinical outcome of peripheral nerve injury. Many efforts are directed towards the fabrication of bioengineered conduits, which could deliver stem cells to the site of injury to promote and guide peripheral nerve regeneration. The aim of this study is to assess whether graphene and related nanomaterials can be useful in the fabrication of such conduits. A comparison is made between graphene oxide (GO) and reduced GO substrates. Our results show that the graphene substrates are highly biocompatible, and the reduced GO substrates are more effective in increasing the gene expression of the biomolecules involved in the regeneration process compared to the other substrates studied. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1098/rsfs.2018.0002 |
| الإتاحة: |
https://doi.org/10.1098/rsfs.2018.0002Test |
| حقوق: |
https://royalsociety.org/journals/ethics-policies/data-sharing-miningTest/ |
| رقم الانضمام: |
edsbas.D418565 |
| قاعدة البيانات: |
BASE |
