Intraoperative monitoring of depth-dependent hemoglobin concentration changes during carotid endarterectomy by time-resolved spectroscopy
| العنوان: | Intraoperative monitoring of depth-dependent hemoglobin concentration changes during carotid endarterectomy by time-resolved spectroscopy |
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| المؤلفون: | Takekane Yamaguchi, Iwae Yu, Yoshinobu Iguchi, Chie Sato, Yoko Hoshi, Yoshihisa Ota, Masahito Nemoto, Mitsuru Seida |
| المصدر: | Applied Optics. 46:2785 |
| بيانات النشر: | The Optical Society, 2007. |
| سنة النشر: | 2007 |
| مصطلحات موضوعية: | Male, Materials science, Spectrophotometry, Infrared, Materials Science (miscellaneous), medicine.medical_treatment, External carotid artery, Hemodynamics, Carotid endarterectomy, Sensitivity and Specificity, Industrial and Manufacturing Engineering, Hemoglobins, Optics, Monitoring, Intraoperative, medicine.artery, medicine, Humans, Carotid Stenosis, Common carotid artery, Business and International Management, skin and connective tissue diseases, Aged, Endarterectomy, Carotid, business.industry, Brain, Reproducibility of Results, Oxygenation, Middle Aged, Light intensity, sense organs, Hemoglobin, Time-resolved spectroscopy, business, Biomedical engineering |
| الوصف: | By measuring the adult human head during carotid endarterectomy, we investigate the depth sensitivity of two methods for deriving the absorption coefficient changes (Dmu(a)) from time-resolved reflectance data to absorption changes in inhomogeneous media: (1) the curve-fitting method based on the diffusion equation (DE-fit method) and (2) the time-independent calculation based on the modified Lambert-Beer law (MLB method). Remarkable differences in the determined values of Dmu(a) caused by clamping the external carotid artery and subsequently clamping the common carotid artery were observed between the methods. The DE-fit method was more sensitive to mu(a) changes in cerebral tissues, whereas the MLB method was rather sensitive to mu(a) changes in the extracerebral tissues. Our results indicated that the DE-fit was useful for monitoring the cerebral blood circulation and oxygenation during neurosurgical operations. In addition, the combined evaluation of mu(a) changes with the DE-fit and MLB methods will provide us with more available information about the hemodynamic changes in the depth direction. |
| تدمد: | 1539-4522 0003-6935 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2dfccc680a28c46118a772e3d28b8eTest https://doi.org/10.1364/ao.46.002785Test |
| رقم الانضمام: | edsair.doi.dedup.....1e2dfccc680a28c46118a772e3d28b8e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15394522 00036935 |
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