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11The Identification of Novel Proteins That Interact With the GLP-1 Receptor and Restrain its Activity
المؤلفون: Kyle W. Sloop, G. Gaisano, S. Kittanakom, Ming Zhang, Aaron D. Showalter, Michael B. Wheeler, Xiaohang Huang, Feihan F. Dai, Junfeng Han, K. Giglou, Li Wei, Victoria Wong, I. Stagljar
المصدر: Molecular Endocrinology. 27:1550-1563
مصطلحات موضوعية: endocrine system, Immunoprecipitation, CHO Cells, Glucagon-Like Peptide-1 Receptor, Chinese hamster, Protein–protein interaction, Mice, Cricetulus, Endocrinology, Ubiquitin, Glucagon-Like Peptide 1, Cricetinae, Insulin-Secreting Cells, Two-Hybrid System Techniques, Insulin Secretion, Cyclic AMP, Receptors, Glucagon, Animals, Humans, Insulin, Protein Interaction Maps, Receptor, Molecular Biology, Original Research, biology, Chinese hamster ovary cell, digestive, oral, and skin physiology, Reproducibility of Results, Colocalization, General Medicine, biology.organism_classification, HEK293 Cells, Biochemistry, biology.protein, Signal transduction, hormones, hormone substitutes, and hormone antagonists, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c47e373cbd33dd93c20d58e8331372Test
https://doi.org/10.1210/me.2013-1047Test -
12
المؤلفون: Patrick M. Sexton, Denise Wootten, Emilia Elizabeth Savage, Laurence J. Miller, Arthur Christopoulos, Cassandra Koole
المصدر: Molecular Endocrinology. 27:1234-1244
مصطلحات موضوعية: medicine.medical_treatment, Molecular Sequence Data, Population, Allosteric regulation, Computational biology, Incretins, Polymorphism, Single Nucleotide, Glucagon-Like Peptide-1 Receptor, Endocrinology, Allosteric Regulation, Glucagon-Like Peptide 1, Drug Discovery, Insulin Secretion, Receptors, Glucagon, medicine, Humans, Insulin, Amino Acid Sequence, education, Receptor, Molecular Biology, education.field_of_study, biology, Drug discovery, Minireviews, General Medicine, Insulin receptor, Glucose, Diabetes Mellitus, Type 2, Biochemistry, biology.protein, Signal transduction, Function (biology), Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c322f605cdfe10ce1ada3915b89cfcTest
https://doi.org/10.1210/me.2013-1116Test -
13
المؤلفون: Manuel Gil-Lozano, Verónica Outeiriño-Iglesias, Eva Vigo, Federico Mallo, Marina Romaní-Pérez, Lucas C. González-Matías
المصدر: Endocrinology. 154:1144-1155
مصطلحات موضوعية: Male, endocrine system, medicine.medical_specialty, Pulmonary Surfactant-Associated Proteins, Amniotic fluid, Offspring, Biology, Dexamethasone, Glucagon-Like Peptide-1 Receptor, Rats, Sprague-Dawley, chemistry.chemical_compound, Fetus, Endocrinology, Glucagon-Like Peptide 1, Pregnancy, Internal medicine, Receptors, Glucagon, medicine, Animals, RNA, Messenger, Receptor, Lung, Glucagon-like peptide 1 receptor, Pulmonary Surfactant-Associated Protein B, Pulmonary Surfactant-Associated Protein A, Venoms, Phenyl Ethers, digestive, oral, and skin physiology, Liraglutide, Nitrofen, Rats, Up-Regulation, Animals, Newborn, chemistry, Exenatide, Female, Peptides, hormones, hormone substitutes, and hormone antagonists, Glucocorticoid, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48b52d9f9eaf6b54031c809f40faeb4Test
https://doi.org/10.1210/en.2012-1786Test -
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المؤلفون: Lene Jessen, Kyle J. Roy, Eric P. Smith, Todd M. Greer, Stephen C. Woods, Jonathan L. Hassel, Randy J. Seeley, David A. D'Alessio, Benedikt A. Aulinger
المصدر: Endocrinology. 153:5735-5745
مصطلحات موضوعية: Male, Heterozygote, endocrine system, medicine.medical_specialty, Pyrrolidines, Dipeptidyl Peptidase 4, medicine.medical_treatment, Transgene, Central nervous system, Adamantane, Mice, Transgenic, Biology, Models, Biological, Glucagon-Like Peptide-1 Receptor, Eating, Mice, Endocrinology, Internal medicine, Nitriles, Receptors, Glucagon, medicine, Animals, Rats, Long-Evans, Vildagliptin, Receptor, Saline, Dipeptidyl peptidase-4, chemistry.chemical_classification, digestive, oral, and skin physiology, Diabetes-Insulin-Glucagon-Gastrointestinal, Glucagon-like peptide-1, Rats, Mice, Inbred C57BL, Enzyme, medicine.anatomical_structure, Gene Expression Regulation, chemistry, Gene Deletion, hormones, hormone substitutes, and hormone antagonists, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723144b16481f4d38c2d310f4bd82cf7Test
https://doi.org/10.1210/en.2012-1358Test -
15
المؤلفون: David M. Keller, Elizabeth A. Clark, Richard H. Goodman
المصدر: Molecular Endocrinology. 26:989-999
مصطلحات موضوعية: Male, medicine.medical_specialty, Transcription, Genetic, Amino Acids, Cyclic, Down-Regulation, RNA polymerase II, Glucagon-Like Peptide-1 Receptor, Rats, Sprague-Dawley, Endocrinology, Downregulation and upregulation, Transcription (biology), Insulin-Secreting Cells, Internal medicine, Insulin Secretion, microRNA, Receptors, Glucagon, medicine, Animals, Insulin, Molecular Biology, Psychological repression, Cells, Cultured, Original Research, biology, Venoms, Kinase, Pancreatic islets, Inverted Repeat Sequences, General Medicine, Cyclic AMP-Dependent Protein Kinases, Rats, Cell biology, MicroRNAs, Glucose, medicine.anatomical_structure, biology.protein, Exenatide, Signal transduction, Peptides, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8ad604e888266c530244a6e078d02cTest
https://doi.org/10.1210/me.2011-1205Test -
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المؤلفون: Laura E. Rupprecht, Matthew R. Hayes, Amber L. Alhadeff
المصدر: Endocrinology. 153:647-658
مصطلحات موضوعية: Male, endocrine system, medicine.medical_specialty, Central nervous system, Nucleus accumbens, Biology, Glucagon-Like Peptide-1 Receptor, Nucleus Accumbens, Rats, Sprague-Dawley, Eating, Endocrinology, Glucagon-Like Peptide 1, Internal medicine, Receptors, Glucagon, Solitary Nucleus, medicine, Animals, Hypoglycemic Agents, Neurons, Dose-Response Relationship, Drug, Venoms, Energy Balance-Obesity, Solitary nucleus, Ventral Tegmental Area, digestive, oral, and skin physiology, Solitary tract, Glucagon-like peptide-1, Rats, Ventral tegmental area, medicine.anatomical_structure, Gene Expression Regulation, nervous system, Exenatide, Neuron, Peptides, Nucleus, hormones, hormone substitutes, and hormone antagonists, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a48518fe265f91516bb9dc6104ca74Test
https://doi.org/10.1210/en.2011-1443Test -
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المؤلفون: David Kirakossian, Chi K. Lai, Peter C. Butler, Matthew M. DeNicola, Belinda Gier, Michael W. Yeh
المصدر: The Journal of Clinical Endocrinology & Metabolism. 97:121-131
مصطلحات موضوعية: Male, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Receptor expression, Clinical Biochemistry, Thyroid Gland, Gene Expression, Validation Studies as Topic, Biochemistry, Endocrinology, Glucagon-Like Peptide 1, Cricetinae, Chlorocebus aethiops, Receptors, Glucagon, Medicine, Tissue Distribution, Thyroid cancer, biology, Thyroid, Middle Aged, medicine.anatomical_structure, Thyroid Cancer, Papillary, COS Cells, Female, hormones, hormone substitutes, and hormone antagonists, Adult, endocrine system, medicine.medical_specialty, CHO Cells, Glucagon-Like Peptide-1 Receptor, Thyroid hormone receptor beta, Thyroid carcinoma, Young Adult, Cricetulus, Thyroid peroxidase, Internal medicine, Animals, Humans, Thyroid Neoplasms, Aged, Hyperplasia, business.industry, Carcinoma, Biochemistry (medical), medicine.disease, Carcinoma, Papillary, Carcinoma, Neuroendocrine, C-Cell Hyperplasia, Calcitonin, biology.protein, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9365e73de211445f3b89cfabe42f684cTest
https://doi.org/10.1210/jc.2011-2407Test -
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المؤلفون: David H. Wasserman, Julio E. Ayala, Deanna P. Bracy, Melissa A. Burmeister, Freyja D. James, Daniel J. Drucker
المصدر: Endocrinology. 151:4678-4687
مصطلحات موضوعية: Male, medicine.medical_specialty, Glucose uptake, medicine.medical_treatment, Biology, Carbohydrate metabolism, Glucagon, Article, Glucagon-Like Peptide-1 Receptor, Mice, Endocrinology, Insulin resistance, Internal medicine, Receptors, Glucagon, medicine, Animals, Insulin, Muscle, Skeletal, Protein kinase B, Glucagon-like peptide 1 receptor, Adiposity, Mice, Knockout, Sex Characteristics, medicine.disease, Dietary Fats, Mice, Inbred C57BL, Insulin receptor, Glucose, Liver, biology.protein, Diet, Atherogenic, Female, Insulin Resistance
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65bffa74460d3d90a8e7e39b32530d3cTest
https://doi.org/10.1210/en.2010-0289Test -
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المؤلفون: Lotte, Bjerre Knudsen, Lars Wichmann, Madsen, Søren, Andersen, Kasper, Almholt, Anne S, de Boer, Daniel J, Drucker, Carsten, Gotfredsen, Frederikke Lihme, Egerod, Anne Charlotte, Hegelund, Helene, Jacobsen, Søren Dyring, Jacobsen, Alan C, Moses, Anne-Marie, Mølck, Henriette S, Nielsen, Jette, Nowak, Helene, Solberg, Tu D L, Thi, Milan, Zdravkovic, Ulrik, Moerch
المصدر: Endocrinology. 151:1473-1486
مصطلحات موضوعية: Endocrinology, Diabetes and Metabolism, Receptor expression, Clinical Biochemistry, Thyroid Gland, Gene Expression, Biochemistry, Rats, Sprague-Dawley, Mice, Endocrinology, Glucagon-Like Peptide 1, Cyclic AMP, Receptors, Glucagon, Receptor, Cells, Cultured, In Situ Hybridization, Mice, Knockout, Reverse Transcriptase Polymerase Chain Reaction, Thyroid, Immunohistochemistry, medicine.anatomical_structure, hormones, hormone substitutes, and hormone antagonists, medicine.drug, Endocrine gland, Calcitonin, Agonist, endocrine system, medicine.medical_specialty, medicine.drug_class, Blotting, Western, Radioimmunoassay, Enzyme-Linked Immunosorbent Assay, Biology, Glucagon-Like Peptide-1 Receptor, Cell Line, Species Specificity, Internal medicine, medicine, Animals, Humans, Obesity, RNA, Messenger, Glucagon-like peptide 1 receptor, Cell Proliferation, Dose-Response Relationship, Drug, Liraglutide, Biochemistry (medical), Rats, Macaca fascicularis, Diabetes Mellitus, Type 1
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79b3718a29c823e2c2079c2f1b7e568Test
https://doi.org/10.1210/en.2009-1272Test -
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المؤلفون: Mansoor Husain, Kyoung-Han Kim, Peter H. Backx, Daniel J. Drucker, Meghan Sauvé, Eleftherios P. Diamandis, Kiwon Ban, Chan-Kyung J Cho
المصدر: Endocrinology. 151:1520-1531
مصطلحات موضوعية: Male, Agonist, endocrine system, medicine.medical_specialty, Time Factors, medicine.drug_class, Blotting, Western, Biology, Glucagon-Like Peptide-1 Receptor, Mass Spectrometry, Mice, chemistry.chemical_compound, Endocrinology, Glucagon-Like Peptide 1, Internal medicine, Amide, Receptors, Glucagon, medicine, Animals, Receptor, Protein kinase B, Cells, Cultured, Glucagon-like peptide 1 receptor, Mice, Knockout, Analysis of Variance, Dose-Response Relationship, Drug, Venoms, Myocardium, digestive, oral, and skin physiology, Heart, Recovery of Function, Cytoprotection, Peptide Fragments, Nitric oxide synthase, chemistry, Reperfusion Injury, biology.protein, Exenatide, Signal transduction, Peptides, hormones, hormone substitutes, and hormone antagonists, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53969f09d8273698d4a3ad55c2f456b9Test
https://doi.org/10.1210/en.2009-1197Test