نتائج البحث - "Activation-induced (cytidine) deaminase"

1

Abrogated AID Function Prolongs Survival and Diminishes Renal Pathology in the BXSB Mouse Model of Systemic Lupus Erythematosus

المؤلفون: Alayna N. Hay, John J Wilson, Madison W Richwine, Ashley Potter, Jing Zhu, Caroline M. Leeth, Muneer G. Hasham, Derry C. Roopenian, Tanya LeRoith, Thomas J. Sproule

المصدر: The Journal of Immunology. 204:1091-1100

مصطلحات موضوعية: Lupus erythematosus, biology, business.industry, Lymphocyte, Immunology, Lupus nephritis, Germinal center, medicine.disease, Belimumab, medicine.anatomical_structure, Renal pathology, medicine, Activation-induced (cytidine) deaminase, biology.protein, Immunology and Allergy, skin and connective tissue diseases, business, Nephritis, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::eaac217f10523371cf7951f7881341c5Test
https://doi.org/10.4049/jimmunol.1900501Test

2

CUL7 E3 Ubiquitin Ligase Mediates the Degradation of Activation-Induced Cytidine Deaminase and Regulates the Ig Class Switch Recombination in B Lymphocytes

المؤلفون: Yang Liu, Liyang Wu, Xiancai Ma, Xu Zhang, Yiwen Zhang, Junsong Zhang, Gen Lu, Feng Huang, Haihua Luo, Yuewen Luo, Yanyan Yang, Yixin Zeng, Xiaoping Tang, Hui Zhang, Linghua Li, Qin Liu, Ting Pan

المصدر: The Journal of Immunology. 203:269-281

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408e37f8d1c561b09509507a537e4984Test
https://doi.org/10.4049/jimmunol.1900125Test

3

Isotype-Switched Autoantibodies Are Necessary To Facilitate Central Nervous System Autoimmune Disease in Aicda−/− and Ung−/− Mice

المؤلفون: Dennis S. W. Lee, Lesley A. Ward, Paulina C Drohomyrecky, Junxian Zhang, Jennifer Y. Yam, Eric Lancaster, Leslie Y. T. Leung, Valeria Ramaglia, Georgina Galicia, Jennifer L. Gommerman, Rui Li, Amit Bar-Or, Alberto Martin, Marcus Handy

المصدر: The Journal of Immunology. 201:1119-1130

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ce234c7cd152c0512eadf5aa5448ef8dTest
https://doi.org/10.4049/jimmunol.1700729Test

4

Exacerbated Staphylococcus aureus Foot Infections in Obese/Diabetic Mice Are Associated with Impaired Germinal Center Reactions, Ig Class Switching, and Humoral Immunity

المؤلفون: Christopher W. Farnsworth, Robert A. Mooney, Eric M. Schott, Michael J. Zuscik, Abigail M. Benvie, Steven R. Gill, Edward M. Schwarz, Stephen L. Kates

المصدر: The Journal of Immunology. 201:560-572

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::41caf4d6929c7571267d3f5779690708Test
https://doi.org/10.4049/jimmunol.1800253Test

5

JNK Regulatory Molecule G5PR Induces IgG Autoantibody–Producing Plasmablasts from Peritoneal B1a Cells

المؤلفون: Masahiro Kitabatake, Yoshimi Fukushima, Daisuke Kitamura, Nobuo Sakaguchi, Miho Soma, Takuya Nojima, Tianli Zhang, Kazuhiko Kuwahara

المصدر: The Journal of Immunology. 194:1480-1488

مصطلحات موضوعية: MAP Kinase Signaling System, Immunology, Cell Culture Techniques, Autoimmunity, Enzyme-Linked Immunosorbent Assay, Mice, Transgenic, Spleen, Cell Separation, Mice, Activation-induced (cytidine) deaminase, medicine, Animals, Immunology and Allergy, Protein Phosphatase 2, Peritoneal Cavity, Autoantibodies, B-Lymphocytes, CD40, biology, Reverse Transcriptase Polymerase Chain Reaction, Precursor Cells, B-Lymphoid, Germinal center, Cell Differentiation, Flow Cytometry, Adoptive Transfer, Immunohistochemistry, Molecular biology, Lymphocyte Subsets, In vitro, Mice, Inbred C57BL, medicine.anatomical_structure, Immunoglobulin class switching, Integrin alpha M, Immunoglobulin G, biology.protein, Female, CD5

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8223eda63398d581fcc868c516971938Test
https://doi.org/10.4049/jimmunol.1401127Test

6

Histone Deacetylase Inhibitors Upregulate B Cell microRNAs That Silence AID and Blimp-1 Expression for Epigenetic Modulation of Antibody and Autoantibody Responses

المؤلفون: Guideng Li, Hong Zan, Egest J. Pone, Paolo Casali, Connie Tat, Ken L. Hayama, Tonika Lam, Clayton A. White

المصدر: Journal of immunology (Baltimore, Md. : 1950), vol 193, iss 12

مصطلحات موضوعية: Mice, Inbred MRL lpr, Lymphocyte Activation, Epigenesis, Genetic, Mice, Gene Knockout Techniques, hemic and lymphatic diseases, Plasma cell differentiation, Activation-induced (cytidine) deaminase, 2.1 Biological and endogenous factors, Immunology and Allergy, Aetiology, B-Lymphocytes, Cell Differentiation, Cytidine deaminase, DNA-Binding Proteins, medicine.anatomical_structure, Female, Drug, Biotechnology, Cell Survival, Plasma Cells, Immunology, Lupus, Somatic hypermutation, Regulatory Factor X Transcription Factors, Biology, Autoimmune Disease, Article, Antibodies, Inbred MRL lpr, Dose-Response Relationship, Genetic, Cytidine Deaminase, PRDM1, Immunoglobulin, Genetics, medicine, Animals, Humans, Gene Silencing, Epigenetics, B cell, Autoantibodies, Dose-Response Relationship, Drug, DNA Methylation, Somatic Hypermutation, Immunoglobulin Class Switching, Repressor Proteins, Histone Deacetylase Inhibitors, MicroRNAs, Gene Expression Regulation, Antibody Formation, Cancer research, biology.protein, Somatic Hypermutation, Immunoglobulin, Positive Regulatory Domain I-Binding Factor 1, Histone deacetylase, Transcription Factors, Epigenesis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b52cf6d78599d0e8e79d0f81325b84Test
https://doi.org/10.4049/jimmunol.1401702Test

7

Apurinic/Apyrimidinic Endonuclease 2 Regulates the Expansion of Germinal Centers by Protecting against Activation-Induced Cytidine Deaminase–Independent DNA Damage in B Cells

المؤلفون: Jeroen E. J. Guikema, Daisuke Tsuchimoto, Nada Esa, Yusaku Nakabeppu, Robert T. Woodland, Erin K. Linehan, Carol E. Schrader

المساهمون: CCA -Cancer Center Amsterdam, Pathology

المصدر: Journal of immunology (Baltimore, Md., 193(2), 931-939. American Association of Immunologists

مصطلحات موضوعية: DNA damage, DNA repair, Immunology, Activation-induced (cytidine) deaminase, biology.protein, Immunology and Allergy, Somatic hypermutation, Germinal center, AP site, Cytidine deaminase, Base excision repair, Biology, Molecular biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5768c00732ac4dcffa653377f74cd85cTest
https://doi.org/10.4049/jimmunol.1400002Test

8

AID and Caspase 8 Shape the Germinal Center Response through Apoptosis

المؤلفون: Jennifer L. Gommerman, Dania Haddad, Ahmad Zaheen, Olga L. Rojas, Bryant Boulianne, Alberto Martin, Razq Hakem, Thanh Nguyen, Anat Kapelnikov, Conglei Li

المصدر: The Journal of Immunology. 191:5840-5847

مصطلحات موضوعية: Plasma Cells, Immunology, B-Lymphocyte Subsets, Receptors, Antigen, B-Cell, Somatic hypermutation, Apoptosis, Plasma cell, Caspase 8, Affinity maturation, Mice, Mice, Congenic, Cytidine Deaminase, medicine, Centroblasts, Activation-induced (cytidine) deaminase, Animals, Immunology and Allergy, DNA Breaks, Double-Stranded, Antigens, Clonal Selection, Antigen-Mediated, B cell, Mice, Knockout, biology, Autoimmune Lymphoproliferative Syndrome, Immunologic Deficiency Syndromes, Germinal center, Germinal Center, Adoptive Transfer, Immunoglobulin Class Switching, Molecular biology, Mice, Inbred C57BL, medicine.anatomical_structure, Radiation Chimera, biology.protein, Immunization, Somatic Hypermutation, Immunoglobulin, Cell Division

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c952ad13ba067fd244da01f2fa75a75eTest
https://doi.org/10.4049/jimmunol.1301776Test

9

Induction of Activation-Induced Cytidine Deaminase–Targeting Adaptor 14-3-3γ Is Mediated by NF-κB–Dependent Recruitment of CFP1 to the 5′-CpG-3′–Rich 14-3-3γ Promoter and Is Sustained by E2A

المؤلفون: Zhenming Xu, Guideng Li, Paolo Casali, Egest J. Pone, Tonika Lam, Thach Mai, J’aime Moehlman

المصدر: The Journal of Immunology. 191:1895-1906

مصطلحات موضوعية: biology, Immunology, chemical and pharmacologic phenomena, Promoter, Cytidine deaminase, Molecular biology, Chromatin, Histone, CpG site, biology.protein, Activation-induced (cytidine) deaminase, Immunology and Allergy, H3K4me3, Histone methyltransferase complex

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::03ff077a95ebeb80da09f00cb84b8e9cTest
https://doi.org/10.4049/jimmunol.1300922Test

10

E2A Expression Stimulates Ig Hypermutation

المؤلفون: Ulrike Schoetz, Manuela Cervelli, Yan-Dong Wang, Jean-Marie Buerstedde, Petra Fiedler

المساهمون: Schoetz, U, Cervelli, Manuela, Wang, Yd, Fiedler, P, Buerstedde, Jm

المصدر: The Journal of Immunology. 177:395-400

مصطلحات موضوعية: Genetic Markers, DNA, Complementary, activation-induced cytidine deaminase, Molecular Sequence Data, Immunology, Ig hypermutation, Receptors, Antigen, B-Cell, Somatic hypermutation, DT 40 cell, Cell Line, Avian Proteins, chemistry.chemical_compound, E2A gene, Transcription (biology), Cytidine Deaminase, Activation-induced (cytidine) deaminase, Animals, Immunology and Allergy, Gene silencing, Gene Silencing, Enhancer, Gene, E12 protein, Base Sequence, biology, Genetic Complementation Test, Cytidine, Sequence Analysis, DNA, Cytidine deaminase, Molecular biology, Clone Cells, E47 protein, chemistry, biology.protein, Immunoglobulin Light Chains, Somatic Hypermutation, Immunoglobulin, TCF Transcription Factors, Chickens

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372c52f92fdfa6ef710faac4ad3162bbTest
https://doi.org/10.4049/jimmunol.177.1.395Test

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