دورية أكاديمية
Novel Mutants of the Aubergine Gene
| العنوان: | Novel Mutants of the Aubergine Gene |
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| المؤلفون: | Şahin, H. Bahar, Karataş, Ömer Faruk, Specchia, Valeria, Di Tommaso, Silvia D., Diebold, Celine, Bozzetti, Maria Pia, Giangrande, Angela |
| بيانات النشر: | Taylor & Francis Inc |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Aubergine, Argonaute, Crystal-stellate, Knockout mutant, Mutagenesis, piRNA, Sterility |
| الوصف: | Aubergine is an RNA-binding protein of the Piwi clade functioning in germline in the piRNA pathway that silences transposons and repetitive sequences. Several mutations of this gene exist but they mostly result in truncated proteins or correspond to mutations that also affect neighboring genes. We have generated complete aubergine knock-out mutants that do not disrupt the neighboring genes. These novel mutants are characterized by PCR and sequencing. Their nature is confirmed by female sterility and by the presence of crystals in testes common to the aubergine loss of function mutations. These mutants provide novel and more appropriate tools for the study of the piRNA pathway that controls genome stability. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1933-6934 1933-6942 |
| العلاقة: | Fly; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://hdl.handle.net/20.500.12469/535Test; https://doi.org/10.1080/19336934.2016.1174355Test; 81; 90; 10; WOS:000381309100004; 2-s2.0-84975801480 |
| DOI: | 10.1080/19336934.2016.1174355 |
| الإتاحة: | https://doi.org/20.500.12469/535Test https://doi.org/10.1080/19336934.2016.1174355Test https://hdl.handle.net/20.500.12469/535Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.11DDBC22 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 19336934 19336942 |
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| DOI: | 10.1080/19336934.2016.1174355 |