دورية أكاديمية
Evaluation of a comprehensive pre-procedural screening protocol for COVID-19 in times of a high SARS CoV-2 prevalence: a prospective cross-sectional study
| العنوان: | Evaluation of a comprehensive pre-procedural screening protocol for COVID-19 in times of a high SARS CoV-2 prevalence: a prospective cross-sectional study |
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| المؤلفون: | Björn Stessel, Ina Callebaut, Fréderic Polus, Laurien Geebelen, Stefan Evers, Jean-Paul Ory, Koen Magerman, Geert Souverijns, Geert Braeken, Dirk Ramaekers, Janneke Cox |
| المصدر: | Annals of Medicine, Vol 53, Iss 1, Pp 337-344 (2021) |
| بيانات النشر: | Taylor & Francis Group, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | COVID-19, ambulant screening, screening protocol, Medicine |
| الوصف: | AbstractBackground To minimise the risk of COVID-19 transmission, an ambulant screening protocol for COVID-19 in patients before admission to the hospital was implemented, combining the SARS CoV-2 reverse-transcriptase polymerase chain reaction (RT-PCR) on a nasopharyngeal swab, a chest computed tomography (CT) and assessment of clinical symptoms. The aim of this study was to evaluatethe diagnostic yield and the proportionality of this pre-procedural screeningprotocol.Methods In this mono-centre, prospective, cross-sectional study, all patients admitted to the hospital between 22nd April 2020 until 14th May 2020 for semi-urgent surgery, haematological or oncological treatment, or electrophysiological investigationunderwent a COVID-19 screening 2 days before their procedure. At a 2-week follow-up, the presence of clinical symptoms was evaluated by telephone as a post-hoc evaluation of the screening approach.Combined positive RT-PCR assay and/or positive chest CT was used as gold standard. Post-procedural outcomes of all patients diagnosed positive for COVID-19 were assessed.Results In total,528 patients were included of which 20 (3.8%) were diagnosed as COVID-19 positive and 508 (96.2%) as COVID-19 negative. 11 (55.0%) of COVID-19 positive patients had only a positive RT-PCR assay, 3 (15.0%) had only a positive chest CT and 6 (30%) had both a positive RT-PCR assay and chest CT. 10 out of 20 (50.0%) COVID-19 positive patients reported no single clinical symptom at the screening. At 2 week follow-up, 50% of these patients were still asymptomatic. 37.5% of all COVID-19 negative patients were symptomatic at screening. In the COVID-19 negative group without symptoms at screening, 78 (29.3%) patients developed clinical symptoms at a 2-week follow-up.Conclusion This study suggests that routine chest CT and assessment of self-reported symptoms have limited value in the preprocedural COVID-19 screening due to low sensitivity and/or specificity. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 07853890 1365-2060 0785-3890 |
| العلاقة: | https://doaj.org/toc/0785-3890Test; https://doaj.org/toc/1365-2060Test |
| DOI: | 10.1080/07853890.2021.1878272 |
| الوصول الحر: | https://doaj.org/article/f2731685d21f4113bf2467c8e4b2cab2Test |
| رقم الانضمام: | edsdoj.f2731685d21f4113bf2467c8e4b2cab2 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 07853890 13652060 |
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| DOI: | 10.1080/07853890.2021.1878272 |