دورية أكاديمية
Economic evaluation of second measles containing vaccine (MCV) dose: a systematic review of available evidence
العنوان: | Economic evaluation of second measles containing vaccine (MCV) dose: a systematic review of available evidence |
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المؤلفون: | Samuel Bawa, Abrham Wondimu, Maarten J. Postma, Raymond Hutubessy, Marinus van Hulst |
المصدر: | Expert Review of Vaccines, Vol 23, Iss 1, Pp 655-673 (2024) |
بيانات النشر: | Taylor & Francis Group, 2024. |
سنة النشر: | 2024 |
المجموعة: | LCC:Internal medicine |
مصطلحات موضوعية: | Model-based, health economic evaluation studies, second measles containing vaccine (MCV2), systematic review, Decision making, Internal medicine, RC31-1245 |
الوصف: | Introduction The global measles incidence has decreased from 145 to 49 cases per 1 million population from 2000 to 2018, but evaluating the economic benefits of a second measles-containing vaccine (MCV2) is crucial. This study reviewed the evidence and quality of economic evaluation studies to guide MCV2 introduction.Methods The systematic review of model-based economic evaluation studies was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The search yielded 2231 articles, with 876 duplicates removed and 1355 articles screened, with nine studies included for final analysis.Results Six studies reported a positive benefit–cost ratio with one resulting in net savings of $11.6 billion, and two studies estimated a 2-dose MMR vaccination program would save $119.24 to prevent one measles case, and a second dose could prevent 9,200 cases at 18 months, saving $548.19 per case. The most sensitive variables were the discount rate and vaccination administration cost.Conclusions Two MCV doses or a second opportunity with an additional dose of MCV were highly cost-beneficial and resulted in substantial cost savings compared to a single routine vaccine. But further research using high-quality model-based health economic evaluation studies of MCV2 should be made available to decision-makers.PROSPERO Registration CRD42020200669 |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 14760584 1744-8395 1476-0584 |
العلاقة: | https://doaj.org/toc/1476-0584Test; https://doaj.org/toc/1744-8395Test |
DOI: | 10.1080/14760584.2024.2367451 |
الوصول الحر: | https://doaj.org/article/f4dde6663d364afeb9ed639b92d868b9Test |
رقم الانضمام: | edsdoj.f4dde6663d364afeb9ed639b92d868b9 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 14760584 17448395 |
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DOI: | 10.1080/14760584.2024.2367451 |