دورية أكاديمية
Platelet-to-albumin ratio: a risk factor associated with technique failure and mortality in peritoneal dialysis patients
| العنوان: | Platelet-to-albumin ratio: a risk factor associated with technique failure and mortality in peritoneal dialysis patients |
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| المؤلفون: | Yuqi Yang, Jing Yuan, Lu Liu, Shuwen Qie, Li Yang, Zha Yan |
| المصدر: | Renal Failure, Vol 43, Iss 1, Pp 1359-1367 (2021) |
| بيانات النشر: | Taylor & Francis Group, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Diseases of the genitourinary system. Urology |
| مصطلحات موضوعية: | platelet-to-albumin ratio, technique failure, mortality, peritoneal dialysis, Diseases of the genitourinary system. Urology, RC870-923 |
| الوصف: | Background Peritoneal dialysis (PD) patients have a high incidence of poor clinical outcomes, which is related to the inflammatory and nutritional status of this population. Platelet-to-albumin ratio (PAR), recently identified as a useful biomarker to monitor inflammation and nutrition, can predict a poor prognosis in various diseases. The aim of this study was to investigate the association between PAR and technique failure and mortality in PD patients. Methods This single-center retrospective study enrolled 405 PD patients from 1 January 2011 to 31 December 2019 and collected complete demographic characteristics, clinical laboratory baseline data. The outcomes were technique failure and mortality. The associations between PAR and technique failure, death were analyzed by Cox proportional hazard models and competing risk regression models with kidney transplantation as a competing event. The areas under the curve (AUC) of receiver-operating characteristic analysis were used to determine the predictive values of PAR for technique failure and mortality. Results During a median follow-up period of 24.0 (range, 4.0–91.0) months, 139 (34.3%) PD patients experienced technique failure, 61 (15.1%) PD patients died. The patients with higher PAR levels had increased risk of technique failure and mortality. After adjustment for confounding factors, we found that high PAR levels were risk factor for both technique failure (subdistribution hazard ratio [SHR] 1.775; 95%CI, 1.157–2.720; p = 0.033] and mortality [SHR 3.710; 95%CI, 1.870–7.360; p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0886-022X 1525-6049 0886022X |
| العلاقة: | https://doaj.org/toc/0886-022XTest; https://doaj.org/toc/1525-6049Test |
| DOI: | 10.1080/0886022X.2021.1977319 |
| الوصول الحر: | https://doaj.org/article/772e9b6b93304fd4b451a038abde5922Test |
| رقم الانضمام: | edsdoj.772e9b6b93304fd4b451a038abde5922 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 0886022X 15256049 |
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| DOI: | 10.1080/0886022X.2021.1977319 |