دورية أكاديمية
Autophagy-independent effects of autophagy-related-5 (Atg5) on exosome production and metastasis
| العنوان: | Autophagy-independent effects of autophagy-related-5 (Atg5) on exosome production and metastasis |
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| المؤلفون: | Huishan Guo, Remy Sadoul, Derrick Gibbings |
| المصدر: | Molecular & Cellular Oncology, Vol 5, Iss 3 (2018) |
| بيانات النشر: | Taylor & Francis Group, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | autophagy, exosomes, v1v0-atpase, acidification, metastasis, biology of malignant cells, mechanisms of oncogenesis and tumor progression, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Autophagy-related-5 (Atg5) and Autophagy-related-16-Like-1 (Atg16L1) canonically participate in autophagy. Recent research demonstrates that apart from this, they also control production of extracellular vesicles called exosomes by regulating acidification of late endosomes. Atg5-mediated exosome production increased migration and metastasis of breast cancer cells suggesting exosomes may perform some functions ascribed to autophagy. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2372-3556 23723556 |
| العلاقة: | https://doaj.org/toc/2372-3556Test |
| DOI: | 10.1080/23723556.2018.1445941 |
| الوصول الحر: | https://doaj.org/article/ab7976e5b68445dbba7b4b920e534e98Test |
| رقم الانضمام: | edsdoj.b7976e5b68445dbba7b4b920e534e98 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23723556 |
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| DOI: | 10.1080/23723556.2018.1445941 |