دورية أكاديمية
Effect of mechanical strain on human limbal epithelial cells in vitro
| العنوان: | Effect of mechanical strain on human limbal epithelial cells in vitro |
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| المؤلفون: | Oh, Joo Youn, Jung, Kyoung Ah, Kim, Mee Kum, Wee, Won Ryang, Lee, Jin Hak |
| المساهمون: | 오주연, 정경아, 김미금, 위원량, 이진학 |
| بيانات النشر: | Taylor & Francis |
| سنة النشر: | 2006 |
| المجموعة: | Seoul National University: S-Space |
| مصطلحات موضوعية: | Blotting, Western, Cell Adhesion Molecules/*biosynthesis, Cell Shape, Cells, Cultured, Enzyme-Linked Immunosorbent Assay, Epithelial Cells/*physiology, Extracellular Matrix/*metabolism, Fibronectins/*biosynthesis, Humans, Limbus Corneae/*cytology, Stress, Mechanical |
| الوصف: | PURPOSE: To investigate the effects of the mechanical cyclic strain on the extracellular matrix (ECM) production by cultivated human limbal epithelial cells (HLECs) in vitro. METHODS: HLECs were repetitively stretched and relaxed by 20% of their original length. Morphology of HLECs was observed, and concentrations of fibronectin and laminin V were measured. RESULTS: The strained HLECs were elongated and aligned perpendicular to the direction of force. Fibronectin and laminin V were highly expressed in the strain group compared with the control. CONCLUSIONS: Cyclic strain induces the synthesis of fibronectin and laminin V in cultivated HLECs. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | Curr Eye Res. 2006 Dec;31(12):1015-20.; 0271-3683 (Print); http://www.informaworld.com/smpp/content~db=all?content=10.1080/02713680601038832Test; http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17169839Test; https://hdl.handle.net/10371/15704Test |
| DOI: | 10.1080/02713680601038832 |
| الإتاحة: | https://doi.org/10.1080/02713680601038832Test https://hdl.handle.net/10371/15704Test http://www.informaworld.com/smpp/content~db=all?content=10.1080/02713680601038832Test http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17169839Test |
| رقم الانضمام: | edsbas.DA59EA5E |
| قاعدة البيانات: | BASE |
| DOI: | 10.1080/02713680601038832 |
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