دورية أكاديمية

Diagnostic Accuracy of Gene X-pert MTB/RIF for Tuberculous Pleural Effusion Compared to Adenosine Deaminase (ADA) at Haji Adam Malik General Hospital Medan

التفاصيل البيبلوغرافية
العنوان: Diagnostic Accuracy of Gene X-pert MTB/RIF for Tuberculous Pleural Effusion Compared to Adenosine Deaminase (ADA) at Haji Adam Malik General Hospital Medan
المؤلفون: Muhammad Zainul A, Fajrinur Syahrani, Siagian, Parluhutan, Eyanoer, Putri Chairani
المصدر: Sumatera Medical Journal; Vol. 2 No. 2 (2019): Sumatera Medical Journal (SUMEJ); 79 - 84 ; 2622-1357 ; 2622-9234
بيانات النشر: Talenta Publisher
سنة النشر: 2019
المجموعة: Talenta Publisher (E-Journals, Universitas Sumatera Utara)
مصطلحات موضوعية: Gene Xpert MTB/RIF, Tuberculous Pleural Effusion, Adenosine Deaminase
الوصف: Indonesia is one of the few countries in the world with very high burden of tuberculosis (TB). Tubercular pleural effusion (Pleural TB) is the most common form of extra-pulmonary TB, however the remains a common clinical challenge. This research from May 2017 through September 2017 a total of 42 patients with exudative lymphocytic pleural effusions suspected to pleural tuberculosis were enrolled in this study. Adenosine deaminase (ADA) and Gene X-pert were examined from pleural fluid. Diagnosis was made clinically or based from sputum/pleural fluid culture. The result of this research showed out of all participants, 64,3% (27/42) had ADA in positive level (>40 IU/L) and 31% (13/24) had Gene X-pert positive Mycobacterium Tb. The Gene X-pert sensitivity was 40.7% with specificity 86.6%, PPV and NPV were 44.8% and 57.1% respectively. Kappa Compatibility study show that Gene X-pert point was 0.227 (p 0.066). The usefulness of Gene X-pert to diagnose pleural TB is limited by its poor sensitivity. Gene X-pert cannot be used as single diagnostic tool for tuberculous pleural effusion
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: English
العلاقة: https://talenta.usu.ac.id/smj/article/view/1067/630Test; https://talenta.usu.ac.id/smj/article/view/1067Test
الإتاحة: https://talenta.usu.ac.id/smj/article/view/1067Test
حقوق: Copyright (c) 2019 Sumatera Medical Journal
رقم الانضمام: edsbas.DC289023
قاعدة البيانات: BASE