التفاصيل البيبلوغرافية
| العنوان: |
Is the Shock Index Associated with Adverse Outcomes among Geriatric Patients with COVID-19 in the Emergency Department Triage? |
| المؤلفون: |
Chien-Chieh Hsieh, Man-Ju Ting, Chung-Ta Chang, Kuang-Chau Tsai, Yi-You Huang, Fu-ShanJaw, Chieh-Min Fan, Jen-Tang Sun, Yuan-Hui Wu |
| المصدر: |
International Journal of Gerontology; Jul2023, Vol. 17 Issue 3, p177-182, 6p |
| مصطلحات موضوعية: |
INTENSIVE care units, C-reactive protein, BIOMARKERS, STATISTICS, COVID-19, MEDICAL triage, HOSPITAL emergency services, BODY weight, SCIENTIFIC observation, CONFIDENCE intervals, PREDICTIVE tests, INTUBATION, FERRITIN, SODIUM, VITAL signs, AGE distribution, MULTIPLE regression analysis, SHOCK (Pathology), RETROSPECTIVE studies, PATIENTS, RESPIRATORY measurements, PULSE oximetry, OXYGEN saturation, TERTIARY care, MANN Whitney U Test, RISK assessment, COMPARATIVE studies, HOSPITAL admission & discharge, T-test (Statistics), DESCRIPTIVE statistics, LACTATE dehydrogenase, CHI-squared test, RESEARCH funding, RECEIVER operating characteristic curves, DATA analysis software, ODDS ratio, DATA analysis, SENSITIVITY & specificity (Statistics), LONGITUDINAL method, PULSE (Heart beat), ALANINE aminotransferase, FIBRIN fibrinogen degradation products, EARLY diagnosis, COMORBIDITY, OLD age |
| مصطلحات جغرافية: |
TAIWAN |
| مستخلص: |
Background: The COVID-19 outbreak presents challenges to the emergency care system. Advanced age is a risk factor formortality. This study aimed to investigate whether the shock index (SI) is an early pre- dictor of adverse outcomes in geriatric patients with COVID-19. Methods: Patients aged ≤ 60 yearswith COVID-19 betweenMay 1, 2021, and February 1, 2022,were in- cluded in a retrospective cohort study. These patients were divided into two groups based on ICU ad- mission. Variables were compared for the two groups. The receiver operating characteristic analysis of the SI and age--SI (ASI) was used to detect deteriorating outcomes early. Results: In total, 156 patients were included, and the mean age was 68.52 ± 7.25 years. ICU admission, intubation, andmortality were recorded in 46 (29.49%), 32 (20.51%), and 16 (10.26%) patients, respec- tively. Themean body weight, pulse rate, respiratory rate, pulse oximetry, SI, and ASI were significantly different between the two groups (p = 0.018, 0.032, 0.007, < 0.001, 0.004, and 0.007, respectively). CRP, LDH, ALT, ferritin, D-dimer, and sodiumlevels were significantly associated with ICU admission. Regard- ing ICU admission, intubation, and mortality, the areas under the curve (AUC) of the SI and ASI showed acceptable discrimination. The predictive power of the ASI was significantly higher than that of the SI for mortality (AUC difference, 0.088 ± 0.036 (95% CI 0.017--0.160); p = 0.016). Conclusion: The ASI is a useful triage tool for mortality prediction in geriatric patients with COVID-19. The SI and ASI can be used in conjunction with vital signs, oxygen saturation, and laboratory biomarkers for the early detection of ICU admission. [ABSTRACT FROM AUTHOR] |
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