Xylanilyticolides A–C, Three New Compounds from Cultures of the Actinomycete Promicromonospora xylanilytica YIM 61515
| العنوان: | Xylanilyticolides A–C, Three New Compounds from Cultures of the Actinomycete Promicromonospora xylanilytica YIM 61515 |
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| المؤلفون: | Zhen-Xiong Wang, Li-Hua Xu, Tao Feng, Rong Huang, Shen Qin, Huan Sun, Zheng-Hui Li, He-Ping Chen, Ji-Kai Liu |
| المصدر: | Natural Products and Bioprospecting, Vol 8, Iss 2, Pp 91-95 (2018) Natural Products and Bioprospecting |
| بيانات النشر: | SpringerOpen, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | 0301 basic medicine, Xylanilyticolides, Stereochemistry, Cytotoxicity, Pharmacology toxicology, Plant Science, Toxicology, medicine.disease_cause, 01 natural sciences, Biochemistry, Analytical Chemistry, 03 medical and health sciences, lcsh:Botany, Ic50 values, medicine, Pharmacology, 010405 organic chemistry, Chemistry, Actinomycete, Organic Chemistry, Promicromonospora xylanilytica, 0104 chemical sciences, lcsh:QK1-989, 030104 developmental biology, Plant biochemistry, Original Article, Two-dimensional nuclear magnetic resonance spectroscopy, Human cancer, Food Science |
| الوصف: | Three new lactones, xylanilyticolides A–C (1–3), were isolated from cultures of the actinomycete Promicromonospora xylanilytica YIM 61515. Their structures were elucidated by 1D and 2D NMR spectroscopic data in conjunction with HRESIMS analysis. Compound 1 exhibited potent cytotoxicities against five human cancer cell lines HL-60, A-549, SMMC-7721, MCF-7 and SW480 with the IC50 values of 3.9, 15.2, 11.2, 5.9, and 4.7 μM, respectively. Graphical Abstract Electronic supplementary material The online version of this article (10.1007/s13659-018-0154-1) contains supplementary material, which is available to authorized users. |
| اللغة: | English |
| تدمد: | 2192-2209 2192-2195 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9538273687b7feb043e0200eff81b402Test http://link.springer.com/article/10.1007/s13659-018-0154-1Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....9538273687b7feb043e0200eff81b402 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 21922209 21922195 |
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