دورية أكاديمية
Cytogenetic analysis in patients with primary myelodysplastic syndromes in leukaemic transformation. A report on 94 cases. Groupe Français de Cytogénétique Hématologique (GFCH)
| العنوان: | Cytogenetic analysis in patients with primary myelodysplastic syndromes in leukaemic transformation. A report on 94 cases. Groupe Français de Cytogénétique Hématologique (GFCH) |
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| المؤلفون: | Brest, D, Rivière, D, Pluchon-Rivière, E, Talmant, P, Pedron, M, Lespinasse, J, Raynaud, S, Taillan, B, Thyss, A, Bayle, J, Ayraud, N, Mugneret, F, Verdier, J, Eclache, V, Lai, JL, Fenaux, P, Zandecki, M, Vandenakker, J, Perot, C, Michaux, Lucienne, Michaux, JL, Berger, R, Jonvaux, P, Charrin, C, Dastugue, N, Lafage, M, Mozziconacci, MJ, Brunel, V, Arnulet, C, Sainty, D, Uetwiller, F, Ruch, JV, Oberling, F, Gregoire, MJ, Buisine, J, Guerci, A, Bernheim, A, Venuat, AM, Groupe Français de Cytogénétique Hématologique |
| بيانات النشر: | Springer-Verlag France |
| سنة النشر: | 1996 |
| المجموعة: | KU Leuven: Lirias |
| مصطلحات موضوعية: | Adolescent, Adult, Aged, 80 and over, Anemia, Refractory, with Excess of Blasts, Child, Chromosome Aberrations, Female, Humans, Karyotyping, Leukemia, Myeloid, Acute, Male, Middle Aged, Myelodysplastic Syndromes, Retrospective Studies, Translocation, Genetic |
| الوصف: | A series of 94 patients presenting primary refractory anaemia with excess of blasts in transformation or acute myeloid leukaemia occurring after a myelodysplastic stage was submitted to retrospective cytogenetic analysis by the Groupe Français de Cytogénétique Hématologique. The aim of this collaborative study was to analyze the patterns of chromosome abnormalities appearing in primary myelodysplastic syndromes (MDS) in leukaemic transformation. As previously described in the literature, the most common chromosome aberrations involved del(5q), -7, +8, 17, 11, 12p and del(20q), while abnormalities of chromosome 17p were more frequently detected during the leukaemic transformation of MDS. The translocations t(2;3) (p22-23;q26-28) and whole arm t(17;18) were confirmed to be nonrandom events in these myeloid disorders. ; status: published |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1269-3286 1279-8509 |
| العلاقة: | Hematology and Cell Therapy vol:38 issue:2 pages:177-81; https://lirias.kuleuven.be/handle/123456789/587077Test |
| الإتاحة: | https://lirias.kuleuven.be/handle/123456789/587077Test |
| رقم الانضمام: | edsbas.E72024B9 |
| قاعدة البيانات: | BASE |
| تدمد: | 12693286 12798509 |
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