High-carotenoid maize: development of plant biotechnology prototypes for human and animal health and nutrition
| العنوان: | High-carotenoid maize: development of plant biotechnology prototypes for human and animal health and nutrition |
|---|---|
| المؤلفون: | Gemma Arjó, Daniela Zanga, Jose A. Moreno, Changfu Zhu, Juan Pedro Ferrio, Gemma Farré, Roxana Savin, Matilde Eizaguirre, Eduardo Angulo, Teresa Capell, Richard M. Twyman, Xavier Matias-Guiu, Ramona N. Pena, Paul Christou, Joan Estany, J. Lloveras, Gustavo A. Slafer, Marc Tor, Ramon Albajes, Carmina Nogareda, Gerhard Sandmann, Joana Díaz-Gómez, A. Michelena, Carlos Cantero-Martínez, Manuel Portero-Otin, Jordi Voltas, Carmen López, Joaquín Serrano, Nuria Eritja |
| المصدر: | Repositorio Abierto de la UdL Universitad de Lleida Dipòsit Digital de la UB Universidad de Barcelona Recercat. Dipósit de la Recerca de Catalunya instname |
| بيانات النشر: | Springer Verlag, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | 0301 basic medicine, Egg production, Carotenoides, Plant Science, Biology, 03 medical and health sciences, Carotenoid, 2. Zero hunger, chemistry.chemical_classification, Genetically modified maize, Plantes transgèniques, Corn, Animal health, business.industry, Transgenic plants, Trout feeding, food and beverages, Poultry production, Carotenoids, Biotechnology, Maize, Blat de moro, 030104 developmental biology, chemistry, business |
| الوصف: | Carolight® is a transgenic maize variety that accumulates extraordinary levels of carotenoids, including those with vitamin A activity. The development of Carolight® maize involved the technical implementation of a novel combinatorial transformation method, followed by rigorous testing for transgene expression and the accumulation of different carotenoid molecules. Carolight® was envisaged as a way to improve the nutritional health of human populations that cannot access a diverse diet, but this ultimate humanitarian application can only be achieved after extensive testing for safety, agronomic performance and nutritional sufficiency. In this article, we chart the history of Carolight® maize focusing on its development, extensive field testing for agronomic performance and resistance to pests and pathogens, and feeding trials to analyze its impact on farm animals (and their meat/dairy products) as well as animal models of human diseases. We also describe more advanced versions of Carolight® endowed with pest-resistance traits, and other carotenoid-enhanced maize varieties originating from the same series of initial transformation experiments. Finally we discuss the further steps required before Carolight® can fulfil its humanitarian objectives, including the intellectual property and regulatory constraints that lie in its path. European Research Council Advanced Grant (BIOFORCE) and Proof of Concept Grant (Multinutrient Maize) to PC; Spanish Ministry of Economy and Competitiveness (AGL2014-53970-C2-1-R, AGL2015-65846-R, BIO2014-54426-P and BIO2014-54441-P); RecerCaixa project PC084082; Catalan Autonomous Community 2014 SGR 1296 Agricultural Biotechnology Research Group and Agrotecnio Research Center. JDG thanks the UdL for a Ph.D. fellowship. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1690db7176e6b755360e2bf03c2c2efTest https://hdl.handle.net/10459.1/62539Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....d1690db7176e6b755360e2bf03c2c2ef |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |