دورية أكاديمية
Evaluation of 5-fluorouracil degradation rate and pharmacogenetic profiling to predict toxicity following adjuvant capecitabine
| العنوان: | Evaluation of 5-fluorouracil degradation rate and pharmacogenetic profiling to predict toxicity following adjuvant capecitabine |
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| المؤلفون: | ROBERTO, MICHELA, ROMITI, ADRIANA, BOTTICELLI, ANDREA, MAZZUCA, FEDERICA, Lionetto, Luana, GENTILE, Giovanna, Paris, Ida, FALCONE, ROSA, BASSANELLI, MARIA, DI PIETRO, FRANCESCA ROMANA, ONESTI, CONCETTA ELISA, ANSELMI, ELISABETTA, MACRINI, SERENA, SIMMACO, Maurizio, MARCHETTI, PAOLO |
| المساهمون: | Roberto, Michela, Romiti, Adriana, Botticelli, Andrea, Mazzuca, Federica, Lionetto, Luana, Gentile, Giovanna, Paris, Ida, Falcone, Rosa, Bassanelli, Maria, DI PIETRO, FRANCESCA ROMANA, Onesti, CONCETTA ELISA, Anselmi, Elisabetta, Macrini, Serena, Simmaco, Maurizio, Marchetti, Paolo |
| بيانات النشر: | Springer Verlag |
| سنة النشر: | 2017 |
| المجموعة: | Sapienza Università di Roma: CINECA IRIS |
| مصطلحات موضوعية: | adjuvant capecitabine, gene polymorphism, oral fluoropyrimidine, personalized medicine, predictive biomarker, toxicity |
| الوصف: | On account of the lack of predictive biomarkers of toxicity, we investigated whether polymorphisms of genes involved in fluoropyrimidine metabolism and 5-fluorouracil (5-FU) degradation rate were associated with outcomes of adjuvant capecitabine in patients with early stage gastrointestinal cancers. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | STAMPA |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/27864592; info:eu-repo/semantics/altIdentifier/wos/WOS:000392308200004; volume:73; issue:2; firstpage:157; lastpage:164; numberofpages:8; journal:EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY; http://hdl.handle.net/11573/905033Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85009759015; link.springer.de/link/service/journals/00228/index.htm |
| DOI: | 10.1007/s00228-016-2160-8 |
| الإتاحة: | https://doi.org/10.1007/s00228-016-2160-8Test http://hdl.handle.net/11573/905033Test |
| حقوق: | info:eu-repo/semantics/restrictedAccess |
| رقم الانضمام: | edsbas.3DFF878C |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s00228-016-2160-8 |
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