دورية أكاديمية

Brucellosis in pregnancy: results of multicenter ID-IRI study.

التفاصيل البيبلوغرافية
العنوان: Brucellosis in pregnancy: results of multicenter ID-IRI study.
المؤلفون: Inan, Asuman, Erdem, Hakan, Elaldi, Nazif, Gulsun, Serda, Karahocagil, Mustafa K, Pekok, Abdullah U, Ulug, Mehmet, Tekin, Recep, Bosilkovski, Mile, Kaya, Safak, Haykir-Solay, Asli, Demirdal, Tuna, Kaya, Selcuk, Sunnetcioglu, Mahmut, Sener, Alper, Tosun, Selma, Aydin, Emsal, Ural, Serap, Yamazhan, Tansu, Muhcu, Murat, Ayaslioglu, Ergin, Bilgic-Atli, Seval, Erbay, Ayse, Ergen, Pinar, Kadanali, Ayten, Sahin, Suzan, Sahin-Horasan, Elif, Avci, Ali, Cag, Yakup, Beeching, Nicholas
المصدر: European Journal of Clinical Microbiology & Infectious Diseases, Vol 38, Issue 7, pp. 1261-1268.
بيانات النشر: Springer Verlag
سنة النشر: 2019
المجموعة: LSTM Online Archive (Liverpool School of Tropical Medicine)
مصطلحات موضوعية: WC 310 Brucellosis, WQ 200 General works
الوصف: Brucellosis in pregnant women is reported to be associated with obstetric complications (OCs), and adequate data for human brucellosis during pregnancy are largely lacking. We performed this multicenter retrospective cross-sectional study to evaluate the epidemiology, clinical course, treatment responses, and outcomes of brucellosis among pregnant women. The study period comprised a 14-year period from January 2002 to December 2015. All consecutive pregnant women diagnosed with brucellosis in 23 participating hospitals were included. Epidemiological, clinical, laboratory, therapeutic, and outcome data along with the assessment data of the neonate were collected using a standardized questionnaire. Data of 242 patients were analyzed. The OC rate was 14.0% (34/242) in the cohort. Of the 242 women, 219 (90.5%) delivered at term, 3 (1.2%) had preterm delivery, 15 (6.2%) aborted, and 5 (2.1%) had intrauterine fetal demise. Seventeen (7.0%) of the newborns were considered as low birth weight. Spontaneous abortion (6.1%) was the commonest complication. There were no maternal or neonatal deaths and pertinent sequelae or complications were not detected in the newborns. Splenomegaly (p = 0.019), nausea and/or vomiting (p < 0.001), vaginal bleeding (p < 0.001), anemia (blood hemoglobin < 11 g/dL; p < 0.001), high level of serum aspartate aminotransferase (> 41 IU/L; p = 0.025), oligohydramnios on ultrasonography (p = 0.0002), history of taking medication other than Brucella treatment during pregnancy (p = 0.027), and Brucella bacteremia (p = 0.029) were the significant factors associated with OCs. We recommend that pregnant women with OC or with fever should be investigated for brucellosis if they live in or have traveled to an endemic area.
نوع الوثيقة: article in journal/newspaper
اللغة: English
العلاقة: Inan, Asuman, Erdem, Hakan, Elaldi, Nazif, Gulsun, Serda, Karahocagil, Mustafa K, Pekok, Abdullah U, Ulug, Mehmet, Tekin, Recep, Bosilkovski, Mile, Kaya, Safak, Haykir-Solay, Asli, Demirdal, Tuna, Kaya, Selcuk, Sunnetcioglu, Mahmut, Sener, Alper, Tosun, Selma, Aydin, Emsal, Ural, Serap, Yamazhan, Tansu, Muhcu, Murat, Ayaslioglu, Ergin, Bilgic-Atli, Seval, Erbay, Ayse, Ergen, Pinar, Kadanali, Ayten, Sahin, Suzan, Sahin-Horasan, Elif, Avci, Ali, Cag, Yakup and Beeching, Nicholas orcid:0000-0002-7019-8791 (2019) 'Brucellosis in pregnancy: results of multicenter ID-IRI study.'. European Journal of Clinical Microbiology & Infectious Diseases, Vol 38, Issue 7, pp. 1261-1268.
الإتاحة: https://archive.lstmed.ac.uk/10783Test/
رقم الانضمام: edsbas.7E288562
قاعدة البيانات: BASE