دورية أكاديمية
Infective endocarditis in patients with hepatic diseases
| العنوان: | Infective endocarditis in patients with hepatic diseases |
|---|---|
| المؤلفون: | Seminari E., De Silvestri A., Ravasio V., Ludovisi S., Utili R., Petrosillo N., Castelli F., Bassetti M., Barbaro F., Grossi P., Barzaghi N., Rizzi M., Minoli L. |
| المساهمون: | Seminari, E., De Silvestri, A., Ravasio, V., Ludovisi, S., Utili, R., Petrosillo, N., Castelli, F., Bassetti, M., Barbaro, F., Grossi, P., Barzaghi, N., Rizzi, M., Minoli, L. |
| بيانات النشر: | Springer Verlag 233 SPRING ST, NEW YORK, NY 10013 USA |
| سنة النشر: | 2016 |
| المجموعة: | Università degli Studi di Genova: CINECA IRIS |
| مصطلحات موضوعية: | Adult, Aged, Endocarditis, Bacterial, Female, Hospital Mortality, Human, Italy, Liver Disease, Male, Middle Aged, Prognosi, Prospective Studie, Prosthesis-Related Infection, Retrospective Studie, Risk Factor, Staphylococcal Infection, Staphylococcus aureu, Staphylococcus epidermidis |
| الوصف: | Few data have been published regarding the epidemiology and outcome of infective endocarditis (IE) in patients with chronic hepatic disease (CHD). A retrospective analysis of the Studio Endocarditi Italiano (SEI) database was performed to evaluate the epidemiology and outcome of CHD+ patients compared with CHD− patients. The diagnosis of IE was defined in accordance with the modified Duke criteria. Echocardiography, diagnosis, and treatment procedures were in accordance with current clinical practice. Among the 1722 observed episodes of IE, 300 (17.4%) occurred in CHD+ patients. The cause of CHD mainly consisted of chronic viral infection. Staphylococcus aureus was the most common bacterial species in CHD+ patients; the frequency of other bacterial species (S. epidermidis, streptococci, and enterococci) were comparable among the two groups. The percentage of patients undergoing surgery for IE was 38.9 in CHD+ patients versus 43.7 in CHD− patients (p = 0.06). Complications were more common among CHD+ patients (77% versus 65.3%, p < 0.001); embolization (43.3% versus 26.1%, p < 0.001) and congestive heart failure (42% versus 34.1%, p = 0.01) were more frequent among CHD+ patients. Mortality was comparable (12.5% in CHD− and 15% in CHD+ patients). At multivariable analysis, factors associated with hospital-associated mortality were having an infection sustained by S. aureus, a prosthetic valve, diabetes and a neoplasia, and CHD. Being an intravenous drug user (IVDU) was a protective factor and was associated with a reduced death risk. CHD is a factor worsening the prognosis in patients with IE, in particular in patients for whom cardiac surgery was required. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | ELETTRONICO |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/26690071; info:eu-repo/semantics/altIdentifier/wos/WOS:000368813200017; volume:35; firstpage:279; lastpage:284; numberofpages:6; journal:EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES; http://hdl.handle.net/11567/994533Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84955461416 |
| DOI: | 10.1007/s10096-015-2541-4 |
| الإتاحة: | https://doi.org/10.1007/s10096-015-2541-4Test http://hdl.handle.net/11567/994533Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.696917D9 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s10096-015-2541-4 |
|---|