The epidemiologic comparison of Japanese and English osteosarcoma patients by Machinami and Wikremaratschi attempts to elucidate the true incidence and the manifold clinicopathologic aspects of this relatively rare disease. Whether or not the analysis of these two disparate groups of patients from two countries and from only partially overlapping periods of time is epidemiologically fair remains an open question. Nevertheless, the current study reemphasizes the fact that Paget’s disease of bone is practically unknown in Japan and consequently Paget’s sarcomas do not occur in that country.
