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المؤلفون: Drew W. Rasco, Theresa Medina, Pippa Corrie, Anna C. Pavlick, Mark R. Middleton, Paul Lorigan, Chris Hebert, Ruth Plummer, James Larkin, Sanjiv S. Agarwala, Adil I. Daud, Jiaheng Qiu, Viviana Bozon, Michelle Kneissl, Elly Barry, Anthony J. Olszanski
المساهمون: Barry, Elly [0000-0002-6890-2444], Apollo - University of Cambridge Repository
المصدر: Cancer chemotherapy and pharmacology, vol 92, iss 1
مصطلحات موضوعية: Adult, Proto-Oncogene Proteins B-raf, Cancer Research, Skin Neoplasms, Maximum Tolerated Dose, Clinical Trials and Supportive Activities, Phase 1, Toxicology, BRAF, Clinical Research, Neoplasms, Humans, Pharmacology (medical), Oncology & Carcinogenesis, Melanoma, Protein Kinase Inhibitors, Pan-RAF inhibitor, Cancer, Pharmacology, Mitogen-Activated Protein Kinase Kinases, Evaluation of treatments and therapeutic interventions, Neoplasms, Second Primary, Pharmacology and Pharmaceutical Sciences, Second Primary, Oncology, 6.1 Pharmaceuticals, Tovorafenib
وصف الملف: application/pdf; application/zip; text/xml
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6be879ecf897194f5e93f0a32cbcfa4dTest
https://www.repository.cam.ac.uk/handle/1810/350906Test -
2دورية أكاديمية
المؤلفون: Rasco, Drew W, Medina, Theresa, Corrie, Pippa, Pavlick, Anna C, Middleton, Mark R, Lorigan, Paul, Hebert, Chris, Plummer, Ruth, Larkin, James, Agarwala, Sanjiv S, Daud, Adil I, Qiu, Jiaheng, Bozon, Viviana, Kneissl, Michelle, Barry, Elly, Olszanski, Anthony J
مصطلحات موضوعية: BRAF, Melanoma, Pan-RAF inhibitor, Phase 1, Tovorafenib, Adult, Humans, Proto-Oncogene Proteins B-raf, Neoplasms, Skin Neoplasms, Protein Kinase Inhibitors, Second Primary, Mitogen-Activated Protein Kinase Kinases, Maximum Tolerated Dose
وصف الملف: application/pdf; application/zip; text/xml
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المؤلفون: Earl Avramis, Charles Ng, Michael Cerniglia, Helena Escuin-Ordinas, Amanda Lassen, Bjoern Titz, Begonya Comin-Anduix, Mohammad Atefi, Thomas G. Graeber, Antoni Ribas, Deborah J.L. Wong, David Foulad
المصدر: Molecular cancer, vol 14, iss 1
Molecular Cancerمصطلحات موضوعية: MAPK/ERK pathway, Neuroblastoma RAS viral oncogene homolog, Cancer Research, Transcription, Genetic, Apoptosis, GTP Phosphohydrolases, Glycogen Synthase Kinase 3, 0302 clinical medicine, Cyclin D1, Cyclin D3, Melanoma, Cancer, Trametinib, 0303 health sciences, Tumor, MEK inhibitor, Cell Cycle, 3. Good health, Oncology, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Molecular Medicine, raf Kinases, Development of treatments and therapeutic interventions, Signal transduction, Transcription, Signal Transduction, MAP Kinase Signaling System, Oncology and Carcinogenesis, NRAS, Biology, Cell Line, 03 medical and health sciences, Genetic, Cell Line, Tumor, Humans, Oncology & Carcinogenesis, Cell Proliferation, 030304 developmental biology, Glycogen Synthase Kinase 3 beta, Research, Membrane Proteins, MAPK, Mutation, Cancer research, pan-RAF inhibitor
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e320a3c09cf525a3044f85b50b79be40Test
https://doi.org/10.1186/s12943-015-0293-5Test