Correction to: Development of patient-reported outcomes item set to evaluate acute treatment toxicity to pelvic online magnetic resonance-guided radiotherapy
| العنوان: | Correction to: Development of patient-reported outcomes item set to evaluate acute treatment toxicity to pelvic online magnetic resonance-guided radiotherapy |
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| المؤلفون: | Møller, Pia Krause, Pappot, H., Bernchou, U., Schytte, T., Dieperink, K. B. |
| المصدر: | Journal of Patient-Reported Outcomes, Vol 5, Iss 1, Pp 1-1 (2021) Møller, P K, Pappot, H, Bernchou, U, Schytte, T & Dieperink, K B 2021, ' Development of patient-reported outcomes item set to evaluate acute treatment toxicity to pelvic online magnetic resonance-guided radiotherapy ', Journal of patient-reported outcomes, vol. 5, no. 1, 47 . https://doi.org/10.1186/s41687-021-00326-wTest |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | PRO, Acute toxicity, Patient-reported outcomes, Radiotherapy, Health Information Management, Item selection, Health Informatics, Public aspects of medicine, RA1-1270, MR-linac, Online MRgRT, Cancer, Pelvic |
| الوصف: | Background: A new technology in cancer treatment, the MR-linac, provides online magnetic resonance-guided radiotherapy (MRgRT) that combines real-time visualization of the tumor and surrounding tissue with radiation therapy to deliver treatment more accurately. Online MRgRT makes it possible to minimize treatment volume, potentially reducing acute treatment toxicity. Patient-reported outcomes (PRO) add the patient perspective to evaluating treatment toxicity related to new technology. The objective of this mixed-methods study was to develop and explore the content validity of a set of PRO items to evaluate acute pelvic toxicity to radiotherapy including online MRgRT. Methods: A literature review and chart audit were conducted to identify symptomatic adverse events (AEs) to be selected from the Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) library and European Organisation for Research and Treatment of Cancer (EORTC) item library. To validate the content, the item set was applied in a prospective pilot cohort of patients referred for primary pelvic RT with curative intent. Patients reported symptoms weekly during RT (4–8 weeks) and the subsequent 4 weeks. Follow-up reports were collected at 8, 12, and 24 weeks after RT. To ensure symptom coverage clinician-reported toxicity and individual patient interviews were conducted. The symptomatic AEs were included in the final item set if ≥20% of patients reported them. Results: Eighteen acute symptomatic AEs were selected for the initial item set. Forty patients (32 prostate cancer, 8 cervical cancer) were included in the pilot study. Patients with prostate cancer and those with cervical cancer both reported all 18 acute AEs. However, vomiting was not reported by > 20% of patients thus excluded from the item set. Adding a few diagnosis-specific AEs to the final item set was required for both prostate and cervical cancer patients. Conclusions: A PRO item set for patients with pelvic cancer treated with radiotherapy with a curative intent was developed and content validity explored. In the pilot study, the item set captured the most common acute symptomatic AEs for patients with prostate and cervical cancer related to pelvic RT including online MRgRT. Further validation of the content in broader disease sites would be needed in future studies. |
| وصف الملف: | application/pdf |
| تدمد: | 2509-8020 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9506777142fc9c786944512b732c22eaTest https://doi.org/10.1186/s41687-021-00333-xTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....9506777142fc9c786944512b732c22ea |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 25098020 |
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