Effect of conjugated linoleic acid supplementation after weight loss on appetite and food intake in overweight subjects
| العنوان: | Effect of conjugated linoleic acid supplementation after weight loss on appetite and food intake in overweight subjects |
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| المؤلفون: | Marleen M. J. W. Kamphuis, Margriet S. Westerterp-Plantenga, Wim H. M. Saris, M.P.G.M. Lejeune |
| المساهمون: | Humane Biologie, RS: NUTRIM School of Nutrition and Translational Research in Metabolism |
| المصدر: | European Journal of Clinical Nutrition, 57(10), 1268-1274. Nature Publishing Group |
| بيانات النشر: | Springer Science and Business Media LLC, 2003. |
| سنة النشر: | 2003 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Diet, Reducing, media_common.quotation_subject, Conjugated linoleic acid, Appetite, Medicine (miscellaneous), Satiation, Overweight, Placebo, Eating, chemistry.chemical_compound, Animal science, Double-Blind Method, Weight loss, Internal medicine, Weight Loss, medicine, Humans, Linoleic Acids, Conjugated, Obesity, Completely randomized design, media_common, Meal, Nutrition and Dietetics, Dose-Response Relationship, Drug, business.industry, food and beverages, Middle Aged, Endocrinology, chemistry, Dietary Supplements, Female, medicine.symptom, Energy Intake, business, Body mass index |
| الوصف: | Effect of conjugated linoleic acid supplementation after weight loss on appetite and food intake in overweight subjects.Kamphuis MM, Lejeune MP, Saris WH, Westerterp-Plantenga MS.Department of Human Biology, Faculty of Health Sciences, Maastricht University, Maastricht, The Netherlands. M.Kamphuis@hb.unimaas.nlOBJECTIVE: To study the effects of 13 weeks conjugated linoleic acid (CLA) supplementation in overweight subjects on body-weight maintenance, parameters of appetite and energy intake (EI) at breakfast after weight loss. DESIGN: This study had a double-blind, placebo-controlled randomized design. SUBJECTS: A total of 26 men and 28 women (age 37.8+/-7.7 y; body mass index 27.8+/-1.5 kg/m(2)). INTERVENTIONS: Subjects were first submitted to a very-low-calorie diet (VLCD; 2.1 MJ/day) for 3 weeks after which they started with the 13-week intervention period. They either received 1.8 g CLA or placebo per day or 3.6 g CLA or placebo per day. Additionally, subjects of the high dosage intervention replaced their habitual lunch by one meal of a protein-rich, low-energy supplement. EI was measured at breakfast and appetite profile after an overnight fast. RESULTS: The mean body weight loss was 6.9+/-1.7% of their original body weight. Multiple regression analysis showed that at the end of the 13-week intervention, CLA did not have an effect on body weight regain. Feelings of fullness and satiety were increased and feelings of hunger were decreased after 13 weeks intervention by CLA compared to placebo, independent of %body weight regain. However, EI measured at breakfast was not affected by CLA. CONCLUSION: Appetite (hunger, satiety and fullness) was favorably, dose-independently affected by a 13-week consumption of 1.8 or 3.6 g CLA/day. This did not result in a lower EI at breakfast or an improved body-weight maintenance after weight loss. |
| وصف الملف: | application/pdf |
| تدمد: | 1476-5640 0954-3007 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de30072675b72cc0338e52a6f847e900Test https://doi.org/10.1038/sj.ejcn.1601684Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....de30072675b72cc0338e52a6f847e900 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14765640 09543007 |
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