دورية أكاديمية

Effect of coffee and cocoa-based confectionery containing coffee on markers of cardiometabolic health: results from the pocket-4-life project

التفاصيل البيبلوغرافية
العنوان: Effect of coffee and cocoa-based confectionery containing coffee on markers of cardiometabolic health: results from the pocket-4-life project
المؤلفون: Martini, Daniela, Rosi, Alice, Tassotti, Michele, Antonini, Monica, Dall’Asta, Margherita, Bresciani, Letizia, Fantuzzi, Federica, Spigoni, Valentina, Domínguez-Perles, Raúl, Angelino, Donato, Ricci, Cristian, Del Pozo-Luengo, Soledad, Tornel, Pedro Luis, Scazzina, Francesca, Gil-Izquierdo, Angel, Dei Cas, Alessandra, Brighenti, Furio, Bonadonna, Riccardo, Del Rio, Daniele, Mena, Pedro
المساهمون: Soremartec Italia S.r.l.
المصدر: European Journal of Nutrition ; volume 60, issue 3, page 1453-1463 ; ISSN 1436-6207 1436-6215
بيانات النشر: Springer Science and Business Media LLC
سنة النشر: 2020
مصطلحات موضوعية: Nutrition and Dietetics, Medicine (miscellaneous)
الوصف: Purpose Coffee is an important source of bioactive compounds, including caffeine, trigonelline, and phenolic compounds. Several studies have highlighted the preventive effects of coffee consumption on major cardiometabolic (CM) diseases, but the impact of different coffee dosages on markers of CM risk in a real-life setting has not been fully understood. This study aimed to investigate the effect of coffee and cocoa-based confectionery containing coffee consumption on several CM risk factors in healthy subjects. Methods In a three-arm, crossover, randomized trial, 21 volunteers were assigned to consume in a random order for 1 month: 1 cup of espresso coffee/day, 3 cups of espresso coffee/day, and 1 cup of espresso coffee plus 2 cocoa-based products containing coffee, twice per day. At the last day of each treatment, blood samples were collected and used for the analysis of inflammatory markers, trimethylamine N -oxide, nitric oxide, blood lipids, and markers of glucose/insulin metabolism. Moreover, anthropometric parameters and blood pressure were measured. Finally, food consumption during the interventions was monitored. Results After 1 month, energy intake did not change among treatments, while significant differences were observed in the intake of saturated fatty acids, sugars, and total carbohydrates. No significant effect on CM markers was observed following neither the consumption of different coffee dosages nor after cocoa-based products containing coffee. Conclusions The daily consumption of common dosages of coffee and its substitution with cocoa-based products containing coffee showed no effect on CM risk factors in healthy subjects. Trial registration number Registered at clinicaltrials.gov as NCT03166540, May 21, 2017.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1007/s00394-020-02347-5
DOI: 10.1007/s00394-020-02347-5.pdf
DOI: 10.1007/s00394-020-02347-5/fulltext.html
الإتاحة: https://doi.org/10.1007/s00394-020-02347-5Test
حقوق: https://creativecommons.org/licenses/by/4.0Test ; https://creativecommons.org/licenses/by/4.0Test
رقم الانضمام: edsbas.ED90632C
قاعدة البيانات: BASE