Blood urea nitrogen and serum bicarbonate in extremely low birth weight infants receiving higher protein intake in the first week after birth
| العنوان: | Blood urea nitrogen and serum bicarbonate in extremely low birth weight infants receiving higher protein intake in the first week after birth |
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| المؤلفون: | Bonnie E. Stephens, Joseph M. Bliss, Richard Tucker, Maya Balakrishnan |
| المصدر: | Journal of Perinatology. 31:535-539 |
| بيانات النشر: | Springer Science and Business Media LLC, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Fat Emulsions, Intravenous, medicine.medical_specialty, Time Factors, Leukomalacia, Periventricular, Bicarbonate, Physiology, urologic and male genital diseases, Blood Urea Nitrogen, chemistry.chemical_compound, Internal medicine, medicine, Humans, Blood urea nitrogen, Phospholipids, Bronchopulmonary Dysplasia, Retrospective Studies, Gram, Acidosis, Kilogram, urogenital system, business.industry, Infant, Newborn, Obstetrics and Gynecology, Repeated measures design, female genital diseases and pregnancy complications, Soybean Oil, Bicarbonates, Low birth weight, Endocrinology, Parenteral nutrition, chemistry, Infant, Extremely Low Birth Weight, Pediatrics, Perinatology and Child Health, Emulsions, Parenteral Nutrition, Total, Dietary Proteins, medicine.symptom, business, Infant, Premature |
| الوصف: | To determine correlation between early protein administration and serum blood urea nitrogen (BUN) or bicarbonate (HCO(3)(-)) in extremely low birth weight (ELBW) infants during the first week of life.A retrospective review of 154 ELBWs was conducted. Laboratory and nutritional data from postnatal days 1, 4 and 7 were collected. Repeated measures models estimated the relationship of protein intake with BUN and HCO(3)(-) in the first week of life.In total, 359 separate BUN and HCO(3)(-) values were analyzed. Each gram per kilogram of protein administered was associated with an increase in mean BUN of 3.3 mg/dl. This effect decreased daily by 2.1 mg/dl. Each gram per kilogram of protein administered was associated with a decrease in mean HCO(3)(-) by 0.9 mmol/l.The association between protein load and BUN is positive but decreasing over time. Protein is associated with a clinically insignificant decrease in HCO(3)(-). Concerns regarding metabolic derangement from early protein administration in ELBWs are unwarranted. |
| تدمد: | 1476-5543 0743-8346 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf3e4ebb4ab68138d51f2d071e9f935Test https://doi.org/10.1038/jp.2010.204Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....eaf3e4ebb4ab68138d51f2d071e9f935 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14765543 07438346 |
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