نتائج البحث

1

Independent replication of advanced brain age in mild cognitive impairment and dementia: detection of future cognitive dysfunction

المصدر: Molecular Psychiatry. 27:5235-5243

مصطلحات موضوعية: Aged, 80 and over, Amyloid beta-Peptides, Apolipoprotein E4, Brain, Middle Aged, Magnetic Resonance Imaging, Cellular and Molecular Neuroscience, Psychiatry and Mental health, Cognition, Alzheimer Disease, Child, Preschool, Positron-Emission Tomography, Humans, Cognitive Dysfunction, Molecular Biology, Aged

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b97cf29b14a90005a101ff7138badfTest
https://doi.org/10.1038/s41380-022-01728-yTest

2

MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer’s disease pathogenesis

المؤلفون: Bin Zhang, Jianwei Hou, Min Huang, Sabrina Ng, Gregory A. Elder, Li Zhu, Mary Sano, Farida El Gaamouch, Julia Tcw, Jiqing Cao, Vahram Haroutunian, Adriana Pero, Larry Zhang, Lei Guo, Alison Goate, Dongming Cai

المصدر: Molecular Psychiatry

مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, medicine.medical_specialty, Microarray, Apolipoprotein E4, Mice, Transgenic, Diseases, Hippocampal formation, Article, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, Cognition, 0302 clinical medicine, Cerebrospinal fluid, Alzheimer Disease, Internal medicine, mental disorders, microRNA, Animals, Humans, Medicine, Cognitive Dysfunction, Induced pluripotent stem cell, Molecular Biology, Amyloid beta-Peptides, business.industry, Human brain, MicroRNAs, Psychiatry and Mental health, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, lipids (amino acids, peptides, and proteins), Lysosomes, business, 030217 neurology & neurosurgery, Homeostasis, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f3137722927cdb5d88afdb078db21dTest
https://doi.org/10.1038/s41380-020-0824-3Test

3

Arterial stiffening acts synergistically with APOE genotype and AD biomarker status to influence memory in older adults without dementia

المؤلفون: Katherine J. Bangen, Christina E. Wierenga, Denis S. Smirnov, Douglas Galasko, Lisa Delano-Wood, David P. Salmon, Mark W. Bondi

المصدر: Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-11 (2021)
Alzheimer's research & therapy, vol 13, iss 1
Alzheimer's Research & Therapy

مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, Oncology, Aging, Apolipoprotein E4, Neurodegenerative, Alzheimer's Disease, Medical and Health Sciences, Cognition, 0302 clinical medicine, 2.1 Biological and endogenous factors, Aetiology, Cognitive decline, Pulse wave velocity, screening and diagnosis, Arterial stiffening, Detection, Vascular risk factors, Neurology, Neurological, Biomarker (medicine), Alzheimer’s disease, RC321-571, medicine.medical_specialty, Genotype, Cognitive Neuroscience, tau Proteins, Neurosciences. Biological psychiatry. Neuropsychiatry, Pulse Wave Analysis, 03 medical and health sciences, Apolipoproteins E, Alzheimer Disease, Clinical Research, Memory, Internal medicine, Behavioral and Social Science, Genetics, Acquired Cognitive Impairment, medicine, Humans, Dementia, Cognitive Dysfunction, Risk factor, RC346-429, Aged, Amyloid beta-Peptides, business.industry, Research, Microcirculation, Prevention, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), medicine.disease, Peptide Fragments, Brain Disorders, 4.1 Discovery and preclinical testing of markers and technologies, 030104 developmental biology, Arterial stiffness, Neurology. Diseases of the nervous system, Neurology (clinical), business, Biomarkers, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075b1bef99d711c8c46004a395f3abc2Test
https://doi.org/10.1186/s13195-021-00851-2Test

4

Menopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition

المؤلفون: Dawn C. Matthews, Eva Schelbaum, Lacey Loughlin, Steven Jett, Orli R. Etingin, Roberta Diaz Brinton, Aneela Rahman, Randolph D. Andrews, Richard S. Isaacson, Jonathan P. Dyke, Mony J. de Leon, Christine A. Ganzer, Grace Jang, Hollie Hristov, Valentina Berti, Lisa Mosconi, Silky Pahlajani

المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Aging, Amyloid, Amyloid beta, Science, Apolipoprotein E4, Neuroimaging, Disease, Article, 03 medical and health sciences, Medical research, 0302 clinical medicine, Alzheimer Disease, medicine, Humans, Effects of sleep deprivation on cognitive performance, Gray Matter, Aged, Brain Mapping, Amyloid beta-Peptides, Multidisciplinary, biology, Cognitive ageing, Brain, Cognition, Human brain, Middle Aged, medicine.disease, Postmenopause, Menopause, 030104 developmental biology, medicine.anatomical_structure, Neurology, Risk factors, Premenopause, biology.protein, Medicine, menopause, MRI, FDG PET, PiB PET, Female, Energy Metabolism, Neuroscience, Biomarkers, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a7d6d57f73fb1640e9c3930b18f648Test
https://doi.org/10.1038/s41598-021-90084-yTest

5

دورية أكاديمية

Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson's disease.

المؤلفون: Liu, Ganqiang, Peng, Jiajie, Liao, Zhixiang, Locascio, Joseph J, Corvol, Jean-Christophe, Zhu, Frank, Dong, Xianjun, Maple-Grødem, Jodi, Campbell, Meghan C, Elbaz, Alexis, Lesage, Suzanne, Brice, Alexis, Mangone, Graziella, Growdon, John H, Hung, Albert Y, Schwarzschild, Michael A, Hayes, Michael T, Wills, Anne-Marie, Herrington, Todd M, Ravina, Bernard, Shoulson, Ira, Taba, Pille, Kõks, Sulev, Beach, Thomas G, Cormier-Dequaire, Florence, Alves, Guido, Tysnes, Ole-Bjørn, Perlmutter, Joel S, Heutink, Peter, Amr, Sami S, van Hilten, Jacobus J, Kasten, Meike, Mollenhauer, Brit, Trenkwalder, Claudia, Klein, Christine, Barker, Roger A, Williams-Gray, Caroline H, Marinus, Johan, International Genetics of Parkinson Disease Progression (IGPP) Consortium, Scherzer, Clemens R

مصطلحات موضوعية: Apolipoprotein E4, Cognition, Cognition Disorders, Disease Progression, Genetic Loci, Genetic Predisposition to Disease, Genome-Wide Association Study, Glucosylceramidase, Humans, Longitudinal Studies, Multifactorial Inheritance, Mutation, Parkinson Disease, Proportional Hazards Models, Risk Factors, Survival Analysis, Synapses

وصف الملف: Print-Electronic; application/vnd.openxmlformats-officedocument.wordprocessingml.document

العلاقة: https://www.repository.cam.ac.uk/handle/1810/336223Test

الإتاحة: https://doi.org/10.17863/CAM.83642Test
https://www.repository.cam.ac.uk/handle/1810/336223Test

View record in BASE

6

The association of APOE ε4 with cognitive function over the adult life course and incidence of dementia: 20 years follow-up of the Whitehall II study

المؤلفون: Melina Regy, Aurore Fayosse, Julien Dumurgier, Mika Kivimäki, Archana Singh-Manoux, Alexis Schnitzler, Aline Dugravot, Amin Gharbi-Meliani, Séverine Sabia

المساهمون: Université Paris Cité, Equipe HAL, Rôle de l'intensité, de la durée et des profils d'activité physique mesurés par accéléromètres pour la santé cardiométabolique - - ActivHealth2019 - ANR-19-CE36-0004 - AAPG2019 - VALID, Epidemiology of Ageing and Neurodegenerative diseases [Paris] (EpiAgeing), Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), University College of London [London] (UCL), Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), ANR-19-CE36-0004,ActivHealth,Rôle de l'intensité, de la durée et des profils d'activité physique mesurés par accéléromètres pour la santé cardiométabolique(2019)

المصدر: Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-11 (2021)
Alzheimer's Research & Therapy
Alzheimer's Research and Therapy
Alzheimer's Research and Therapy, 2021, 13 (1), pp.5. ⟨10.1186/s13195-020-00740-0⟩

مصطلحات موضوعية: Adult, Male, Apolipoprotein E, Genotype, Cognitive Neuroscience, Apolipoprotein E4, Population, Neuropsychological Tests, lcsh:RC346-429, lcsh:RC321-571, Cohort Studies, Cognitive aging, Apolipoproteins E, Cognition, Alzheimer Disease, medicine, Humans, Dementia, Effects of sleep deprivation on cognitive performance, education, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, lcsh:Neurology. Diseases of the nervous system, Aged, education.field_of_study, business.industry, Research, Incidence, Hazard ratio, [SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences, Middle Aged, medicine.disease, Cognitive test, Neurology, Female, Neurology (clinical), Cohort study, business, Alzheimer’s disease, [SDV.NEU.SC] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences, Follow-Up Studies, Demography

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::137f4f71c76c459a4fab09f2ff2f62bdTest
https://doi.org/10.1186/s13195-020-00740-0Test

7

The relationship between physical activity, apolipoprotein E ε4 carriage, and brain health

المؤلفون: Federico Ramírez-Toraño, Ana M. López-Sobaler, Belinda M. Brown, Pablo Cuesta, David López-Sanz, Esther Cuadrado-Soto, María Luisa Delgado-Losada, Simon M. Laws, Jaisalmer de Frutos-Lucas, África Peral-Suárez, Ana Barabash, Ricardo Bruña, Ramón López-Higes, Fernando Maestú, Juan Verdejo-Román, Alberto Marcos, Juan M. Serrano, Inmaculada Concepción Rodríguez-Rojo

المساهمون: UAM. Departamento de Psicología Biológica y de la Salud

المصدر: Biblos-e Archivo. Repositorio Institucional de la UAM
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Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-12 (2020)
Alzheimer's Research & Therapy
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid