المؤلفون: Drew W. Rasco, Theresa Medina, Pippa Corrie, Anna C. Pavlick, Mark R. Middleton, Paul Lorigan, Chris Hebert, Ruth Plummer, James Larkin, Sanjiv S. Agarwala, Adil I. Daud, Jiaheng Qiu, Viviana Bozon, Michelle Kneissl, Elly Barry, Anthony J. Olszanski

المساهمون: Barry, Elly [0000-0002-6890-2444], Apollo - University of Cambridge Repository

المصدر: Cancer chemotherapy and pharmacology, vol 92, iss 1

مصطلحات موضوعية: Adult, Proto-Oncogene Proteins B-raf, Cancer Research, Skin Neoplasms, Maximum Tolerated Dose, Clinical Trials and Supportive Activities, Phase 1, Toxicology, BRAF, Clinical Research, Neoplasms, Humans, Pharmacology (medical), Oncology & Carcinogenesis, Melanoma, Protein Kinase Inhibitors, Pan-RAF inhibitor, Cancer, Pharmacology, Mitogen-Activated Protein Kinase Kinases, Evaluation of treatments and therapeutic interventions, Neoplasms, Second Primary, Pharmacology and Pharmaceutical Sciences, Second Primary, Oncology, 6.1 Pharmaceuticals, Tovorafenib

وصف الملف: application/pdf; application/zip; text/xml

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https://www.repository.cam.ac.uk/handle/1810/350906Test

المؤلفون: Victoria G. Woof, Rebecca J. Lee, Paul Lorigan, David P. French

المصدر: Woof, V G, Lee, R J, Lorigan, P & French, D P 2022, ' Circulating tumour DNA monitoring and early treatment for relapse: views from patients with early-stage melanoma. ', British Journal of Cancer, vol. 126, pp. 1450–1456 . https://doi.org/10.1038/s41416-022-01766-xTest

مصطلحات موضوعية: Cancer Research, Oncology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab0e8bfab37e262544cd6aca4c23a722Test
https://doi.org/10.1038/s41416-022-01766-xTest

المؤلفون: Philippa Middlehurst, Nathalie Dhomen, Richard Marais, Gabriela Gremel, John Weightman, Sarah Mills, Jeff Barry, Zena Salih, Avinash Gupta, Elena Galvani, Joshua Tweedy, Paul Lorigan, Antonia Banyard, Piyushkumar A. Mundra, Franziska Baenke, Sara Valpione

المصدر: Nature cancer
Valpione, S, Galvani, E, Tweedy, J, Mundra, P A, Banyard, A, Middlehurst, P, Barry, J, Mills, S, Salih, Z, Weightman, J, Gupta, A, Gremel, G, Baenke, F, Dhomen, N, Lorigan, P C & Marais, R 2020, ' Immune awakening revealed by peripheral T cell dynamics after one cycle of immunotherapy ', Nature Cancer . https://doi.org/10.1038/s43018-019-0022-xTest

مصطلحات موضوعية: Cancer Research, medicine.medical_treatment, T cell, Receptors, Antigen, T-Cell, Peripheral blood mononuclear cell, Article, 03 medical and health sciences, 0302 clinical medicine, Immune system, medicine, Humans, Immunologic Factors, Melanoma, 030304 developmental biology, 0303 health sciences, Manchester Cancer Research Centre, business.industry, ResearchInstitutes_Networks_Beacons/mcrc, T-cell receptor, Immunotherapy, medicine.disease, 3. Good health, Peripheral, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Immunology, Leukocytes, Mononuclear, Skin cancer, business

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a54ef2b0dc1631afba50d0992b93beecTest
https://doi.org/10.1038/s43018-019-0022-xTest

المؤلفون: Nathalie Dhomen, Elena Galvani, Luca Giovanni Campana, Sara Valpione, Sarah Mills, John Weightman, Paul Lorigan, Avinash Gupta, Piyushkumar A. Mundra, Richard Marais, Francesco De Rosa

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Nature Communications

مصطلحات موضوعية: Adult, Male, Skin Neoplasms, Statistical methods, Biopsy, T-Lymphocytes, Science, medicine.medical_treatment, Receptors, Antigen, T-Cell, General Physics and Astronomy, Cancer immunotherapy, Predictive markers, General Biochemistry, Genetics and Molecular Biology, Cohort Studies, Lymphocytes, Tumor-Infiltrating, Biomarkers, Tumor, Humans, Medicine, Author Correction, Melanoma, Aged, Aged, 80 and over, Multidisciplinary, business.industry, Cancer survival, General Chemistry, Middle Aged, Prognosis, T-Cell Receptor Repertoire, Survival Rate, Cancer research, Tumour immunology, Female, Immunotherapy, business, Tumor immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05bd13cf857ce5a417a77188e7d48871Test
https://doi.org/10.1038/s41467-021-24897-wTest

المؤلفون: Fredrik Pontén, Rafael Botella-Estrada, Miguel Vizoso, Ultan McDermott, Jose Luis Manzano, Anna Martínez-Cardús, Catia Moutinho, Joost van den Oord, María Martínez-Iniesta, Alberto Villanueva, Paula Lopez-Serra, August Vidal, Sebastian Moran, Elena Elez, F. Javier Carmona, Julia Liz, Maria Romina Girotti, Holger Heyn, Sonia Guil, Alfonso Berrocal, Paul Lorigan, Dennie T. Frederick, María Teresa Fernández-Figueras, Humberto J. Ferreira, Anna Portela, William M. Gallagher, Richard Marais, Eva Muñoz-Couselo, Keith T. Flaherty, Manel Esteller

المساهمون: Universitat de Barcelona

المصدر: Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Cell Cycle
NATURE MEDICINE
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Europe PubMed Central

مصطلحات موضوعية: Transcriptional Activation, GTPase-activating protein, Immunoprecipitation, Mice, Nude, Editorials: Cell Cycle Features, Biology, Bioinformatics, Methylation, General Biochemistry, Genetics and Molecular Biology, Epigenesis, Genetic, Metastasis, Epigènesi, Metàstasi, Cell Line, Tumor, medicine, Animals, Protein Isoforms, RNA, Messenger, Epigenetics, Neoplasm Metastasis, RNA, Small Interfering, Promoter Regions, Genetic, Proteïnes supressores de tumors, Protein Kinase Inhibitors, Melanoma, GTPase-Activating Proteins, General Medicine, DNA Methylation, Prognosis, medicine.disease, Tumor suppressor protein, ErbB Receptors, Molecular Weight, Treatment Outcome, rab GTP-Binding Proteins, DNA methylation, Disease Progression, Cancer research, Rab, Metilació, Protein Binding, Signal Transduction, Epigenesis

وصف الملف: application/pdf

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https://doi.org/10.1038/nm.3863Test

المؤلفون: Hilary Calvert, Jorge Gallo, Diane Wang, Evan A. Mulligan, Ruth Plummer, R. Dewji, Nicola J. Curtin, Richard H. Wilson, Antonello Abbattista, Neil Steven, Mark R. Middleton, Lucy Scott, Paul Lorigan

المصدر: Cancer Chemotherapy and Pharmacology. 71:1191-1199

مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Indoles, Skin Neoplasms, Dacarbazine, Phases of clinical research, Poly(ADP-ribose) Polymerase Inhibitors, Toxicology, Disease-Free Survival, Young Adult, chemistry.chemical_compound, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Temozolomide, medicine, Humans, Pharmacology (medical), Rucaparib, Melanoma, Aged, Aged, 80 and over, Pharmacology, Performance status, business.industry, Drug Synergism, Middle Aged, medicine.disease, Survival Rate, Treatment Outcome, chemistry, Pharmacodynamics, PARP inhibitor, Immunology, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a5f71944f6e4cad781a2c6e8eb29d9Test
https://doi.org/10.1007/s00280-013-2113-1Test

المؤلفون: Richard Marais, Pippa Corrie, Christian H. Ottensmeier, S Prendergast, Paul Nathan, U P Strauss, Martin Gore, Annette Affolter, M. G. James, David Chao, Thomas Jouary, Mark Harries, I Gibbens, Sylvie Negrier, Tanya Ahmad, Christine Chevreau, E Montegriffo, Paul Lorigan, Timothy Eisen, Caroline Robert

المصدر: British Journal of Cancer

مصطلحات موضوعية: Adult, Male, Niacinamide, Sorafenib, Oncology, Cancer Research, medicine.medical_specialty, Skin Neoplasms, Maximum Tolerated Dose, Pyridines, Dacarbazine, dacarbazine, Dacarbazina, urologic and male genital diseases, Disease-Free Survival, Drug Administration Schedule, combination therapy, First line therapy, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, melanoma, medicine, Humans, heterocyclic compounds, Neoplasm Metastasis, neoplasms, Aged, Advanced melanoma, business.industry, Phenylurea Compounds, Melanoma, Benzenesulfonates, Middle Aged, medicine.disease, female genital diseases and pregnancy complications, digestive system diseases, Surgery, Maximum tolerated dose, Clinical Study, biomarker, Female, Open label, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ead51dcbe7c0874045d9ab40685c07Test
https://doi.org/10.1038/bjc.2011.257Test

المؤلفون: John F. Smyth, Christian H. Ottensmeier, Ulrich Keilholz, Robert E. Hawkins, Klaus Hoffmann, Richard Anderson, Martin Cripps, Dirk Schadendorf, Adam Dangoor, Paul Lorigan, Adrian L. Harris, Joerg Schneider

المصدر: Cancer Immunology, Immunotherapy. 59:863-873

مصطلحات موضوعية: Adult, Male, Cancer Research, medicine.medical_treatment, T cell, Immunology, Medizin, Immunization, Secondary, Epitopes, T-Lymphocyte, Vaccinia virus, CD8-Positive T-Lymphocytes, Lymphocyte Activation, Cancer Vaccines, complex mixtures, Epitope, Interferon-gamma, MART-1 Antigen, Immune system, Antigens, Neoplasm, HLA-A2 Antigen, medicine, Humans, Immunology and Allergy, Neoplasm Metastasis, Melanoma, Aged, Neoplasm Staging, business.industry, ELISPOT, Immunogenicity, Immunotherapy, Middle Aged, medicine.disease, Survival Analysis, Neoplasm Proteins, medicine.anatomical_structure, Tetramer assay, Oncology, Disease Progression, Female, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb67b4203ee7a30cf2109fc100c41077Test
https://doi.org/10.1007/s00262-009-0811-7Test

المؤلفون: Corinne Faivre-Finn, Nick Thatcher, Fiona H Blackhall, Raffaele Califano, L. Aschroft, Sofia Baka, Roberta Ferraldeschi, Paul Lorigan, Paul D. Taylor

المصدر: British Journal of Cancer

مصطلحات موضوعية: Adult, Male, Cancer Research, medicine.medical_specialty, Lung Neoplasms, Anthracycline, Cyclophosphamide, medicine.medical_treatment, cisplatin, Neutropenia, chemotherapy, doxorubicin, Gastroenterology, randomised clinical trial, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Clinical Studies, Antineoplastic Combined Chemotherapy Protocols, small-cell lung cancer, medicine, Humans, Extensive stage, Carcinoma, Small Cell, Lung cancer, Etoposide, Aged, Monitoring, Physiologic, 030304 developmental biology, Aged, 80 and over, 0303 health sciences, Chemotherapy, business.industry, Middle Aged, medicine.disease, Survival Analysis, Carboplatin, 3. Good health, Surgery, Oncology, chemistry, 030220 oncology & carcinogenesis, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc28750c58157ca97e675a971120b98Test
https://doi.org/10.1038/sj.bjc.6604480Test

المؤلفون: Fiona H Blackhall, Nick Thatcher, Richard W. Griffiths, Paul Lorigan

المصدر: Targeted Oncology. 3:205-215

مصطلحات موضوعية: Oncology, Limited Stage, Cancer Research, medicine.medical_specialty, Chemotherapy, business.industry, medicine.medical_treatment, Cancer, Disease, medicine.disease, Malignancy, Small-cell carcinoma, Targeted therapy, Internal medicine, Immunology, medicine, Pharmacology (medical), Lung cancer, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::2fef14489fe0298b32e2bb48cb368985Test
https://doi.org/10.1007/s11523-008-0086-5Test