المؤلفون: Huanyao Gao, Brandon J. Coombes, Duan Liu, Richard M. Weinshilboum, Daniel C. Kim, Zhenqing Ye, Tamas Ordog, Mark A. Frye, Jeong Heon Lee, Thanh Thanh L. Nguyen, Brenna Sharp, Huaizhi Huang, Liewei Wang, Joanna M. Biernacka

المصدر: Molecular Psychiatry. 26:7454-7464

مصطلحات موضوعية: endocrine system, Bipolar Disorder, endocrine system diseases, Induced Pluripotent Stem Cells, Genome-wide association study, Biology, Polymorphism, Single Nucleotide, Transcription Factor 7-Like 2, Body Mass Index, Cellular and Molecular Neuroscience, Humans, SNP, Induced pluripotent stem cell, Glucocorticoids, Molecular Biology, Gene, Gene knockdown, nutritional and metabolic diseases, Psychiatry and Mental health, Diabetes Mellitus, Type 2, Expression quantitative trait loci, Cancer research, RNA, Long Noncoding, Transcription Factor 7-Like 2 Protein, TCF7L2, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ddd61d1c975027ec76dea2023a2267Test
https://doi.org/10.1038/s41380-021-01274-zTest

المؤلفون: Chen Weng, Yan Li, Konstantin Leskov, Fulai Jin, Sisi Lai, Luxin Ke, Anniya Gu, Jian Cui, Haiyan Li, Jiajia Xi

المصدر: Nature metabolism

مصطلحات موضوعية: Endocrinology, Diabetes and Metabolism, Cell fate determination, Biology, Article, Transcriptome, Diabetes mellitus genetics, Insulin-Secreting Cells, Physiology (medical), Insulin Secretion, Diabetes Mellitus, Internal Medicine, Transcriptional regulation, Humans, Cell Lineage, Enhancer, Gene, Embryonic Stem Cells, Regulation of gene expression, Gene Expression Regulation, Developmental, Cell Differentiation, Cell Biology, Embryonic stem cell, Cell biology, Glucose, Gene Knockdown Techniques, Transcription Factor HES-1, Transcription Factor 7-Like 2 Protein, Genes, Switch

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fbf12a2b485d3f50c94b6c0ebfaef7eTest
https://doi.org/10.1038/s42255-020-00314Test-2

المؤلفون: Constanze Lamprecht, Andreas Hecht, Gilles Rauen, Melanie Boerries, Janna Wenzel, Katja Rose, Vivien Freihen, Elham Bavafaye Haghighi, Rebecca Kesselring

المصدر: Oncogene

مصطلحات موضوعية: 0301 basic medicine, endocrine system, Cancer Research, endocrine system diseases, Carcinogenesis, Mitosis, Core Binding Factor Alpha 1 Subunit, Biology, Proto-Oncogene Mas, Article, 03 medical and health sciences, 0302 clinical medicine, Cell Movement, Cancer genomics, Genetics, Humans, Neoplasm Invasiveness, Progenitor cell, Wnt Signaling Pathway, Molecular Biology, Transcription factor, beta Catenin, Tissue homeostasis, Cell Proliferation, Cell adhesion molecule, Effector, Wnt signaling pathway, Growth factor signalling, nutritional and metabolic diseases, Extracellular matrix, Cell cycle, HCT116 Cells, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Cell culture, 030220 oncology & carcinogenesis, Cancer research, Colorectal Neoplasms, Transcription Factor 7-Like 2 Protein, hormones, hormone substitutes, and hormone antagonists

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::251f7c4cb1c9892beeaf5da8673c54b4Test
https://doi.org/10.1038/s41388-020-1259-7Test

المؤلفون: Mu Su, Lan Shao, Shuang Cui, Xiao Han, Ming Liu, Qiong Wu, ShiYou Liu, Hongjuan He

المصدر: Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 3, Pp 1-14 (2021)

مصطلحات موضوعية: Cancer Research, Immunology, Mice, Nude, Fos-Related Antigen-2, Biology, Article, Cancer prevention, Cellular and Molecular Neuroscience, Super-enhancer, Cell Movement, Neoplasms, Animals, Humans, lcsh:QH573-671, Neoplasm Metastasis, Cancer models, Enhancer, Wnt Signaling Pathway, Transcription factor, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, Oncogene, lcsh:Cytology, Receptor, EphA2, Wnt signaling pathway, Cell Biology, HCT116 Cells, Gene Expression Regulation, Neoplastic, Enhancer Elements, Genetic, A549 Cells, Tumor progression, MCF-7 Cells, Cancer research, Phosphatidylinositol 3-Kinase, Proto-Oncogene Proteins c-akt, Transcription Factor 7-Like 2 Protein, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa96a81f92143afe92e4281283d9dafdTest
https://doi.org/10.1038/s41419-021-03538-6Test

المؤلفون: Kunal Karve, Lili Deng, Shirin Bonni, Stuart J. Netherton, Azad Bonni

المصدر: Cell Death and Disease, Vol 11, Iss 8, Pp 1-20 (2020)
Cell Death & Disease

مصطلحات موضوعية: 0301 basic medicine, Gene isoform, Cancer Research, Epithelial-Mesenchymal Transition, endocrine system diseases, Molecular biology, Immunology, Morphogenesis, Article, Cell Line, Transforming Growth Factor beta1, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Transforming Growth Factor beta, Animals, Humans, Protein Isoforms, Smad3 Protein, Epithelial–mesenchymal transition, lcsh:QH573-671, Transcription factor, biology, lcsh:Cytology, Alternative splicing, nutritional and metabolic diseases, Epithelial Cells, Cell Biology, Transforming growth factor beta, Cell biology, Organoids, 030104 developmental biology, 030220 oncology & carcinogenesis, RNA splicing, biology.protein, Signal transduction, Transcription Factor 7-Like 2 Protein, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff8c84683a40d6d758d7e33d6d2ef2bTest
https://doi.org/10.1038/s41419-020-02905-zTest

المؤلفون: Daniel F. Gudbjartsson, Fereidoun Azizi, Erna V. Ivarsdottir, Isleifur Olafsson, Unnur Thorsteinsdottir, Valgerdur Steinthorsdottir, Olof Sigurdardottir, Rafn Benediktsson, Gudmar Thorleifsson, Gudmundur I. Eyjolfsson, Astradur B. Hreidarsson, Hilma Holm, Maryam S. Daneshpour, Arni V Thorsson, Kari Stefansson, Ragnar Bjarnason, Patrick Sulem, Sirous Zeinali, Gunnar Sigurdsson, Snaevar Sigurdsson

المصدر: Nature Genetics. 49:1398-1402

مصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, medicine.medical_specialty, Iceland, Penetrance, Type 2 diabetes, Polymorphism, Single Nucleotide, Body Mass Index, 03 medical and health sciences, Gene Frequency, Risk Factors, Internal medicine, Glucokinase, Genetics, medicine, Humans, Genetic Predisposition to Disease, Allele, Allele frequency, Alleles, Glycated Hemoglobin, biology, Genetic Variation, Fasting, Heritability, medicine.disease, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, Glucose-6-Phosphatase, biology.protein, Female, Transcription Factor 7-Like 2 Protein, TCF7L2, Body mass index, Glucose 6-phosphatase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f339bb65586e022663c8d5c487d6a8dTest
https://doi.org/10.1038/ng.3928Test

المؤلفون: Markus Brown, Immaculada Ponsa, Jordi Camps, Anna Bosch, Maria Calvo, Darawalee Wangsa, Maria Vila-Casadesús, Thomas Ried, Keyvan Torabi, Antoni Castells, Tatiana S. Karpova, Rosa Miró

المصدر: Chromosoma

مصطلحات موضوعية: 0301 basic medicine, Adenocarcinoma, Biology, Article, 03 medical and health sciences, Cell Line, Tumor, Gene density, Gene expression, Genetics, medicine, Chromosomes, Human, Humans, Interphase, Gene, In Situ Hybridization, Fluorescence, Genetics (clinical), Cell Nucleus, Regulation of gene expression, medicine.diagnostic_test, Chromosome, Molecular biology, 030104 developmental biology, Gene Expression Regulation, Chromosome Territory, Colorectal Neoplasms, Transcription Factor 7-Like 2 Protein, Chromosome 22, Signal Transduction, Fluorescence in situ hybridization

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04d181e9da5b8b98ed23b9bbcdc6d1cTest
https://doi.org/10.1007/s00412-017-0629-6Test

المؤلفون: Ayo P. Doumatey, Cristina Pomilla, Elizabeth H. Young, Anubha Mahajan, Mark I. McCarthy, Meng Sun, Ayesha A. Motala, Fraser J. Pirie, Guanjie Chen, Eleanor Wheeler, Ji Chen, Andrew P. Morris, Adebowale Adeyemo, Inês Barroso, Tommy Carstensen, Charles N. Rotimi, Manjinder S. Sandhu

المساهمون: Sandhu, Manjinder [0000-0002-2725-142X], Barroso, Ines [0000-0001-5800-4520], Wheeler, Eleanor [0000-0002-8616-6444], Apollo - University of Cambridge Repository

المصدر: Chen, J, Sun, M, Adeyemo, A, Pirie, F, Carstensen, T, Pomilla, C, Doumatey, A P, Chen, G, Young, E H, Sandhu, M, Morris, A P, Barroso, I, McCarthy, M I, Mahajan, A, Wheeler, E, Rotimi, C N & Motala, A A 2019, ' Genome-wide association study of type 2 diabetes in Africa ', Diabetologia, vol. 62, no. 7, pp. 1204-1211 . https://doi.org/10.1007/s00125-019-4880-7Test
DIABETOLOGIA
Diabetologia

مصطلحات موضوعية: 0301 basic medicine, Genome-wide association study, Genotyping Techniques, Endocrinology, Diabetes and Metabolism, Black People, 030209 endocrinology & metabolism, Locus (genetics), Type 2 diabetes, Biology, Genetic analysis, Polymorphism, Single Nucleotide, Article, White People, 03 medical and health sciences, 0302 clinical medicine, Internal Medicine, medicine, Humans, Genetic Predisposition to Disease, Genetic association, Genetics, Fine-mapping, medicine.disease, Genetic architecture, 3. Good health, Minor allele frequency, 030104 developmental biology, Diabetes Mellitus, Type 2, Africa, Established loci, TCF7L2, Transcription Factor 7-Like 2 Protein

وصف الملف: application/pdf; application/zip; text/xml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26b9ac35fdee2e04abeed161169d97bTest
https://www.repository.cam.ac.uk/handle/1810/294957Test

المؤلفون: Daniel V. LaBarbera, Frederick A Valeriote, Adedoyin D. Abraham, Qiong Zhou, Daniel L. Gustafson, Linfeng Li, A Babalmorad, Stacey M. Bagby, John J. Arcaroli, J Schaack, Wells A. Messersmith, R J Hansen

المصدر: Oncogene

مصطلحات موضوعية: 0301 basic medicine, Chromatin Immunoprecipitation, Cancer Research, Epithelial-Mesenchymal Transition, Biology, DNA-binding protein, Molecular oncology, 03 medical and health sciences, Antigens, Neoplasm, Transcription (biology), Cell Line, Tumor, Genetics, Humans, Neoplasm Invasiveness, Protein Interaction Maps, Epithelial–mesenchymal transition, Neoplasm Metastasis, Molecular Biology, beta Catenin, Cell Proliferation, Wnt signaling pathway, Promoter, TCF4, Molecular biology, Neoplasm Proteins, 3. Good health, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, DNA Topoisomerases, Type II, 030104 developmental biology, Colonic Neoplasms, embryonic structures, Cancer research, Original Article, Transcription Factor 7-Like 2 Protein, Chromatin immunoprecipitation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bbaea30fb50e149a5b2005009eff4bdTest
https://doi.org/10.1038/onc.2016.29Test

المؤلفون: Martijn van de Bunt

المصدر: Diabetologia. 59:2292-2294

مصطلحات موضوعية: 0301 basic medicine, Genetics, Effector, Endocrinology, Diabetes and Metabolism, Locus (genetics), Genome-wide association study, Type 2 diabetes, Human physiology, Biology, ACSL5, medicine.disease, Polymorphism, Single Nucleotide, 03 medical and health sciences, 030104 developmental biology, Diabetes Mellitus, Type 2, Internal Medicine, medicine, Humans, Genetic Predisposition to Disease, TCF Transcription Factors, Transcription Factor 7-Like 2 Protein, TCF7L2, Gene

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdba14fa381eff45d3d32994fa96f0f0Test
https://doi.org/10.1007/s00125-016-4103-4Test