التفاصيل البيبلوغرافية
| العنوان: |
Evaluating the Arteriotomy Size of a New Sutureless Coronary Anastomosis Using a Finite Volume Approach. |
| المؤلفون: |
Crielaard, Hanneke, Hoogewerf, Marieke, van Putte, Bart P., van de Vosse, Frans N., Vlachojannis, Georgios J., Stecher, David, Stijnen, Marco, Doevendans, Pieter A. |
| المصدر: |
Journal of Cardiovascular Translational Research; Aug2023, Vol. 16 Issue 4, p916-926, 11p |
| مستخلص: |
Objectives: The ELANA® Heart Bypass creates a standardized sutureless anastomosis. Hereby, we investigate the influence of arteriotomy and graft size on coronary hemodynamics. Methods: A computational fluid dynamics (CFD) model was developed. Arteriotomy size (standard 1.43 mm2; varied 0.94 – 3.6 mm2) and graft diameter (standard 2.5 mm; varied 1.5 – 5.0 mm) were independent parameters. Outcome parameters were coronary pressure and flow, and fractional flow reserve (FFR). Results: The current size ELANA (arteriotomy 1.43 mm2) presented an estimated FFR 0.65 (39 mL/min). Enlarging arteriotomy increased FFR, coronary pressure, and flow. All reached a maximum once the arteriotomy (2.80 mm2) surpassed the coronary cross-sectional area (2.69 mm2, i.e. 1.85 mm diameter), presenting an estimated FFR 0.75 (46 mL/min). Increasing graft diameter was positively related to FFR, coronary pressure, and flow. Conclusion: The ratio between the required minimal coronary diameter for application and the ELANA arteriotomy size effectuates a pressure drop that could be clinically relevant. Additional research and eventual lengthening of the anastomosis is advised. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
