Coenzyme Q10 in Metabolic syndrome
| العنوان: | Coenzyme Q10 in Metabolic syndrome |
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| المؤلفون: | Juan Diego Hernández-Camacho |
| المصدر: | Coenzyme Q in Aging ISBN: 9783030456412 Digital.CSIC. Repositorio Institucional del CSIC instname |
| بيانات النشر: | Springer Nature, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Coenzyme Q10, Aging, medicine.diagnostic_test, business.industry, Insulin, medicine.medical_treatment, Physiology, Insulin resistance, Disease, medicine.disease, Obesity, Metabolic syndrome, Mitochondria, chemistry.chemical_compound, chemistry, Oxidative stress, Medicine, business, Lipid profile, Sedentary lifestyle |
| الوصف: | Metabolic syndrome (MS) has become a global health issue due to affect a high percentage of people in most of the countries. MS can be defined as the presence of three of the following factors: obesity, high triglyceride and cholesterol levels, low HDL cholesterol, high blood pressure or high fasting plasma glucose. All these factors increase the risk of cardiovascular disease, diabetes type II, some kind of cancers, sleep abnormalities or physical incapacity among other. Several factors have been identified in the aetiology of MS such as dietary patterns, sedentary lifestyle, genetic background, microbiota, socioeconomic status or age. Different treatments have been proposed for the treatment of MS, but, until today, there is no efficient solution. CoQ10 has emerged as a potential way in MS treatment endorsed by several clinical trials have shown improvements in lipid profile, glucose control, insulin homeostasis and hypertension control in MS patients. The molecular mechanism that could explain these improvements would be the antioxidant capacity of CoQ10 inhibiting oxidative stress that it is present in MS. Additionally, the proportion of CoQ10H2 could be also a crucial role in the protection again MS components. Furthermore, CoQ10 administration could be also helpful in the management of mitochondrial dysfunction associated to MS. |
| ردمك: | 978-3-030-45641-2 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451c7c9ab41bb55d912c2cf1384bcdbfTest http://hdl.handle.net/10261/230541Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....451c7c9ab41bb55d912c2cf1384bcdbf |
| قاعدة البيانات: | OpenAIRE |
| ردمك: | 9783030456412 |
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