المؤلفون: Alfredo Iacoangeli, Simon Topp, Benjamin M. Neale, Kevin Eggan, Pamela J. Shaw, Ahmad Al Khleifat, Andrea Byrnes, Sulagna Ghosh, Ammar Al-Chalabi, Bryan J. Traynor, Karen E. Morrison, Marc Gotkine, Rosa Rademakers, David Goldstein, Mike A. Nalls, Michael Benatar, Rebecca Schüle, Evadnie Rampersaud, Claire Churchhouse, Joanne Wuu, Sali M.K. Farhan, Aleksey Shatunov, Stephan Züchner, J. Paul Taylor, Liam Abbott, Christopher Shaw, Daniel P. Howrigan, Mark J. Daly, Jacob L. McCauley, Hemali Phatnani, Gang Wu, Joseph R. Klim, Daniel A. Mordes, Bradley N. Smith, Matthew B. Harms

المساهمون: ALSGENS Consortium, FALS Consortium, Project MinE Consortium, CReATe Consortium

المصدر: Nature neuroscience
Nature reviews / Neuroscience 22(12), 1966-1974 (2019). doi:10.1038/s41593-019-0530-0

مصطلحات موضوعية: 0301 basic medicine, Male, Protein family, SOD1, Protein aggregation, Biology, Article, 03 medical and health sciences, 0302 clinical medicine, genetics [Heat-Shock Proteins], genetics [Molecular Chaperones], Heat shock protein, ddc:570, DNAJC7 protein, human, medicine, genetics [Exome], Humans, Exome, Genetic Predisposition to Disease, Amyotrophic lateral sclerosis, genetics [Genetic Predisposition to Disease], Gene, Exome sequencing, Heat-Shock Proteins, Genetics, General Neuroscience, Neurodegeneration, Amyotrophic Lateral Sclerosis, Genetic Variation, medicine.disease, genetics [Genetic Variation], genetics [Amyotrophic Lateral Sclerosis], 030104 developmental biology, Case-Control Studies, Female, Human medicine, Neuroscience, 030217 neurology & neurosurgery, Molecular Chaperones

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfdf42fde92988d1774056282cad0404Test

المؤلفون: Katerina Placek, Michael Benatar, Joanne Wuu, Evadnie Rampersaud, Laura Hennessy, Vivianna M Van Deerlin, Murray Grossman, David J Irwin, Lauren Elman, Leo McCluskey, Colin Quinn, Volkan Granit, Jeffrey M Statland, Ted M Burns, John Ravits, Andrea Swenson, Jon Katz, Erik P Pioro, Carlayne Jackson, James Caress, Yuen So, Samuel Maiser, David Walk, Edward B Lee, John Q Trojanowski, Philip Cook, James Gee, Jin Sha, Adam C Naj, Rosa Rademakers, The CReATe Consortium, Wenan Chen, Gang Wu, J Paul Taylor, Corey T McMillan

المصدر: EMBO Molecular Medicine, Vol 13, Iss 1, Pp n/a-n/a (2021)

مصطلحات موضوعية: amyotrophic lateral sclerosis, cognition, frontotemporal dementia, machine learning, polygenic score, Medicine (General), R5-920, Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1757-4676Test; https://doaj.org/toc/1757-4684Test

الوصول الحر: https://doaj.org/article/c97ccf4df05c438e987a0ef12c4302e4Test