Neuroendocrine tumours of the female genital tract: a case-based imaging review with pathological correlation
| العنوان: | Neuroendocrine tumours of the female genital tract: a case-based imaging review with pathological correlation |
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| المؤلفون: | Catarina Callé, Filipe Veloso Gomes, Teresa Margarida Cunha, Ana Félix, João Lopes Dias |
| المصدر: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação instacron:RCAAP Europe PubMed Central Insights into Imaging |
| بيانات النشر: | Springer Nature |
| مصطلحات موضوعية: | Female circumcision, Pathology, medicine.medical_specialty, endocrine system diseases, Review, Neuroendocrine tumors, Well-differentiated neuroendocrine tumours (NETs), Small-cell carcinoma, Neuroendocrine Cells, medicine, Radiology, Nuclear Medicine and imaging, Large-cell neuroendocrine carcinoma, Carcinoma, Small Cell, Pathological correlation, Neuroradiology, Small cell carcinoma, business.industry, HSJ IMA, Large cell neuroendocrine carcinoma, Poorly differentiated neuroendocrine carcinomas (NECs), medicine.disease, Carcinoid, Carcinoma, Neuroendocrine, Neuroendocrine Tumors, business |
| الوصف: | BACKGROUND: Both primary and secondary gynaecological neuroendocrine (NE) tumours are uncommon, and the literature is scarce concerning their imaging features. METHODS: This article reviews the epidemiological, clinical and imaging features with pathological correlation of gynaecological NE tumours. RESULTS: The clinical features of gynaecological NE tumours are non-specific and depend on the organ of origin and on the extension and aggressiveness of the disease. The imaging approach to these tumours is similar to that for other histological types and the Revised International Federation of Gynecology and Obstetrics (FIGO) Staging System also applies to NE tumours. Neuroendocrine tumours were recently divided into two groups: poorly differentiated neuroendocrine carcinomas (NECs) and well-differentiated neuroendocrine tumours (NETs). NECs include small cell carcinoma and large cell neuroendocrine carcinoma, while NETs account for typical and atypical carcinoids. Cervical small cell carcinoma and ovarian carcinoid are the most common gynaecological NE tumours. The former typically behaves aggressively; the latter usually behaves in a benign fashion and tends to be confined to the organ. CONCLUSION: While dealing with ovarian carcinoids, extra-ovarian extension, bilaterality and multinodularity raise the suspicion of metastatic disease. NE tumours of the endometrium and other gynaecological locations are very rare. TEACHING POINTS: • Primary or secondary neurondocrine (NE) tumours of the female genital tract are rare. • Cervical small cell carcinoma and ovarian carcinoids are the most common gynaecological NE tumours. • Cervical small cell carcinomas usually behave aggressively. • Ovarian carcinoids tend to behave in a benign fashion. • The imaging approach to gynaecological NE tumours and other histological types is similar. |
| اللغة: | English |
| تدمد: | 1869-4101 |
| DOI: | 10.1007/s13244-014-0378-5 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd89d4ff4bff0553b4f29fe50d75101Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....1fd89d4ff4bff0553b4f29fe50d75101 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18694101 |
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| DOI: | 10.1007/s13244-014-0378-5 |