التفاصيل البيبلوغرافية
| العنوان: |
Design and methodology of the Swiss Transplant Cohort Study (STCS): a comprehensive prospective nationwide long-term follow-up cohort. |
| المؤلفون: |
Koller, Michael, Delden, Christian, Müller, Nicolas, Baumann, Philippe, Lovis, Christian, Marti, Hans-Peter, Fehr, Thomas, Binet, Isabelle, Geest, Sabina, Bucher, Heiner, Meylan, Pascal, Pascual, Manuel, Steiger, Jürg |
| المصدر: |
European Journal of Epidemiology; Apr2013, Vol. 28 Issue 4, p347-355, 9p |
| مصطلحات موضوعية: |
TRANSPLANTATION of organs, tissues, etc., FOLLOW-up studies (Medicine), LONGITUDINAL method, PROCUREMENT of organs, tissues, etc., HEALTH outcome assessment, COHORT analysis |
| مصطلحات جغرافية: |
SWITZERLAND |
| مستخلص: |
In Switzerland, organ procurement is well organized at the national-level but transplant outcomes have not been systematically monitored so far. Therefore, a novel project, the Swiss Transplant Cohort Study (STCS), was established. The STCS is a prospective multicentre study, designed as a dynamic cohort, which enrolls all solid organ recipients at the national level. The features of the STCS are a flexible patient-case system that allows capturing all transplant scenarios and collection of patient-specific and allograft-specific data. Beyond comprehensive clinical data, specific focus is directed at psychosocial and behavioral factors, infectious disease development, and bio-banking. Between May 2008 and end of 2011, the six Swiss transplant centers recruited 1,677 patients involving 1,721 transplantations, and a total of 1,800 organs implanted in 15 different transplantation scenarios. 10 % of all patients underwent re-transplantation and 3% had a second transplantation, either in the past or during follow-up. 34% of all kidney allografts originated from living donation. Until the end of 2011 we observed 4,385 infection episodes in our patient population. The STCS showed operative capabilities to collect high-quality data and to adequately reflect the complexity of the post-transplantation process. The STCS represents a promising novel project for comparative effectiveness research in transplantation medicine. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
