Vestibulo-perceptual influences upon the vestibulo-spinal reflex
| العنوان: | Vestibulo-perceptual influences upon the vestibulo-spinal reflex |
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| المؤلفون: | Paul H. Strutton, Sofia Nousi, Adolfo M. Bronstein, Qadeer Arshad, Rhannon Lobo, Angela Bonsu |
| المصدر: | Experimental Brain Research |
| بيانات النشر: | Springer Berlin Heidelberg, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | STIMULATION, medicine.medical_specialty, MOTION, genetic structures, Vestibular evoked myogenic potential, media_common.quotation_subject, Audiology, Vestibulo-spinal reflexes, Arousal, Perception, Sensation, medicine, otorhinolaryngologic diseases, Humans, Vestibular-evoked myogenic potentials, Postural Balance, 11 Medical and Health Sciences, media_common, Vestibular system, Science & Technology, Neurology & Neurosurgery, General Neuroscience, Neurosciences, Reflex, Vestibulo-Ocular, Gaze, Vestibular Evoked Myogenic Potentials, humanities, 17 Psychology and Cognitive Sciences, Vection, Reflex, Neurosciences & Neurology, Brainstem, sense organs, Vestibule, Labyrinth, EVOKED MYOGENIC POTENTIALS, Psychology, Life Sciences & Biomedicine, Head, RESPONSES, Research Article |
| الوصف: | The vestibular system facilitates gaze and postural stability via the vestibulo-ocular (VOR) and vestibulo-spinal reflexes, respectively. Cortical and perceptual mechanisms can modulate long-duration VOR responses, but little is known about whether high-order neural phenomena can modulate short-latency vestibulo-spinal responses. Here, we investigate this by assessing click-evoked cervical vestibular myogenic-evoked potentials (VEMPS) during visual roll motion that elicited an illusionary sensation of self-motion (i.e. vection). We observed that during vection, the amplitude of the VEMPs was enhanced when compared to baseline measures. This modulation in VEMP amplitude was positively correlated with the subjective reports of vection strength. That is, those subjects reporting greater subjective vection scores exhibited a greater increase in VEMP amplitude. Control experiments showed that simple arousal (cold-induced discomfort) also increased VEMP amplitude but that, unlike vection, it did not modulate VEMP amplitude linearly. In agreement, small-field visual roll motion that did not induce vection failed to increase VEMP amplitude. Taken together, our results demonstrate that vection can modify the response of vestibulo-collic reflexes. Even short-latency brainstem vestibulo-spinal reflexes are influenced by high-order mechanisms, illustrating the functional importance of perceptual mechanisms in human postural control. As VEMPs are inhibitory responses, we argue that the findings may represent a mechanism whereby high-order CNS mechanisms reduce activity levels in vestibulo-collic reflexes, necessary for instance when voluntary head movements need to be performed. |
| اللغة: | English |
| تدمد: | 1432-1106 0014-4819 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a2e33c5780d594e6003fc0d4547bafTest http://europepmc.org/articles/PMC8282553Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....73a2e33c5780d594e6003fc0d4547baf |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14321106 00144819 |
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