دورية أكاديمية
RAGE is a multiligand receptor of the immunoglobulin superfamily: implications for homeostasis and chronic disease
| العنوان: | RAGE is a multiligand receptor of the immunoglobulin superfamily: implications for homeostasis and chronic disease |
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| المؤلفون: | Bucciarelli L, Wendt T, Rong L, Lalla E, Hofmann MA, Goova MT, Taguchi A, Yan SF, Yan SD, Stern DM, Schmidt AM |
| المساهمون: | L. Bucciarelli, T. Wendt, L. Rong, E. Lalla, M. Hofmann, M. Goova, A. Taguchi, S. Yan, D. Stern, A. Schmidt |
| بيانات النشر: | Springer |
| سنة النشر: | 2002 |
| المجموعة: | The University of Milan: Archivio Istituzionale della Ricerca (AIR) |
| مصطلحات موضوعية: | Atherosclerosi, Cancer, Diabete, Immunoglobulin, Inflammation, Receptor, Superfamily, Vasculopathy, Settore MED/13 - Endocrinologia |
| الوصف: | Receptor for AGE (RAGE) is a member of the immunoglobulin superfamily that engages distinct classes of ligands. The biology of RAGE is driven by the settings in which these ligands accumulate, such as diabetes, inflammation, neurodegenerative disorders and tumors. In this review, we discuss the context of each of these classes of ligands, including advance glycation end-products, amyloid beta peptide and the family of beta sheet fibrils, S100/calgranulins and amphoterin. Implications for the role of these ligands interacting with RAGE in homeostasis and disease will be considered. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/12222959; info:eu-repo/semantics/altIdentifier/wos/WOS:000177629600003; volume:59; issue:7; firstpage:1117; lastpage:1128; numberofpages:12; journal:CELLULAR AND MOLECULAR LIFE SCIENCES; https://hdl.handle.net/2434/1045711Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-18544375186 |
| DOI: | 10.1007/s00018-002-8491-x |
| الإتاحة: | https://doi.org/10.1007/s00018-002-8491-xTest https://hdl.handle.net/2434/1045711Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.A2071A87 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s00018-002-8491-x |
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