دورية أكاديمية
The histopathological diagnosis of atypical meningioma: glass slide versus whole slide imaging for grading assessment
| العنوان: | The histopathological diagnosis of atypical meningioma: glass slide versus whole slide imaging for grading assessment |
|---|---|
| المؤلفون: | Ammendola, Serena, Bariani, Elena, Eccher, Albino, Capitanio, Arrigo, Ghimenton, Claudio, Pantanowitz, Liron, Parwani, Anil, Girolami, Ilaria, Scarpa, Aldo, Barresi, Valeria |
| بيانات النشر: | Linköpings universitet, Avdelningen för neurobiologi Linköpings universitet, Medicinska fakulteten Klinisk patologi Univ Verona, Italy Univ & Hosp Trust Verona, Italy Univ Michigan, MI 48109 USA Ohio State Univ, OH 43210 USA Cent Hosp Bolzano, Italy Univ Verona, Italy; Univ & Hosp Trust Verona, Italy Univ Verona, Italy; Polyclin GB Rossi, Italy SPRINGER |
| سنة النشر: | 2021 |
| المجموعة: | Linköping University Electronic Press (LiU E-Press) |
| مصطلحات موضوعية: | Atypical meningioma, Whole slide imaging, Digital, Recurrence, Reproducibility, Urology and Nephrology, Urologi och njurmedicin |
| الوصف: | Limited studies on whole slide imaging (WSI) in surgical neuropathology reported a perceived limitation in the recognition of mitoses. This study analyzed and compared the inter- and intra-observer concordance for atypical meningioma, using glass slides and WSI. Two neuropathologists and two residents assessed the histopathological features of 35 meningiomas-originally diagnosed as atypical-in a representative glass slide and corresponding WSI. For each histological parameter and final diagnosis, we calculated the inter- and intra-observer concordance in the two viewing modes and the predictive accuracy on recurrence. The concordance rates for atypical meningioma on glass slides and on WSI were 54% and 60% among four observers and 63% and 74% between two neuropathologists. The inter-observer agreement was higher using WSI than with glass slides for all parameters, with the exception of high mitotic index. For all histological features, we found median intra-observer concordance of >= 79% and similar predictive accuracy for recurrence between the two viewing modes. The higher concordance for atypical meningioma using WSI than with glass slides and the similar predictive accuracy for recurrence in the two modalities suggest that atypical meningioma may be safely diagnosed using WSI. ; Funding Agencies|Universita degli Studi di Verona. FUR 2019, University of Verona, Italy |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | Virchows Archiv, 0945-6317, 2021, 478, s. 747-756; http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-172503Test; PMID 33305338; ISI:000597987500001 |
| DOI: | 10.1007/s00428-020-02988-1 |
| الإتاحة: | https://doi.org/10.1007/s00428-020-02988-1Test http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-172503Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.9F04357 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s00428-020-02988-1 |
|---|