التفاصيل البيبلوغرافية
| العنوان: |
Natural killer/T-cell lymphoma-associated hemophagocytic syndrome: A case report. |
| المؤلفون: |
LIJUAN HAN, MINGZHI ZHANG, LING LI, LEI ZHANG, JINGJING WU, XIN LI, XINHUA WANG, YOUNG, KEN. H., XIAORUI FU, WANG MA, ZHENCHANG SUN, XUDONG ZHANG, YU CHANG, ZHI QIAO |
| المصدر: |
Oncology Letters; 2014, Vol. 8 Issue 2, p886-890, 5p |
| مصطلحات موضوعية: |
KILLER cells, T cells, LYMPHOMAS, RARE diseases, PANCYTOPENIA |
| مستخلص: |
Natural killer (NK)/T-cell lymphoma-associated hemophagocytic syndrome (HPS) is a rare and fatal disease with no optimal treatment. The present study reports the clinical features, diagnosis and treatment process of three patients with relapsed NK/T-cell lymphoma-associated HPS. All of the patients were classified as Ann Arbor stage IV and presented with a poor performance status. Two patients were successfully treated with a pegaspargase-containing combination regimen and one patient succumbed due to serious complications. These cases indicate that for patients with a history of lymphoma, the diagnosis of HPS should be considered when patients present with progressive high fever, pancytopenia and liver dysfunction. Early identification and effective treatments, including pegaspargase-based regimens are essential for an enhanced prognosis. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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