التفاصيل البيبلوغرافية
| العنوان: |
Autophagy: A novel therapeutic target for hepatocarcinoma (Review). |
| المؤلفون: |
ZHANGGUI WANG1, WEIDONG HAN1, XINBING SUI1, YONG FANG1, HONGMING PAN1 panhm2013@gmail.com |
| المصدر: |
Oncology Letters. 2014, Vol. 7 Issue 5, p1345-1351. 7p. |
| مصطلحات موضوعية: |
*LIVER cancer, *LIVER cancer patients, *AUTOPHAGY, *CANCER treatment, *CARCINOGENESIS |
| مستخلص: |
Autophagy is a highly conserved intracellular degradation process and plays an important role in hepatocarcinogenesis. Available data show that autophagy is involved in anti-hepatocarcinoma (HCC) therapies. Autophagy regulation involves a novel target for overcoming therapeutic resistance and sensitizing HCC to currently therapeutic methods. This is a systematic review on the interface of autophagy and the development of HCC and outlining the role of autophagy in current anti-HCC approaches. Understanding the significance of autophagy in anti-HCC therapy may offer a novel therapeutic target for improving anti-cancer efficacy and prolong survival for HCC patients. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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