Second primary extracolonic cancers in Japanese hereditary nonpolyposis colorectal cancer
| العنوان: | Second primary extracolonic cancers in Japanese hereditary nonpolyposis colorectal cancer |
|---|---|
| المؤلفون: | Yosuke Seo, Akinobu Taketomi, Hideo Baba, Tsuyoshi Saito, Shunji Kohnoe, Hirotsugu Tomoda |
| المصدر: | Oncology Reports. |
| بيانات النشر: | Spandidos Publications, 1998. |
| سنة النشر: | 1998 |
| مصطلحات موضوعية: | Adult, Male, Reoperation, Cancer Research, medicine.medical_specialty, Colorectal cancer, Rectum, Ovary, Gastroenterology, Ureter, Japan, Stomach Neoplasms, Internal medicine, Epidemiology, medicine, Humans, Aged, Ovarian Neoplasms, Rectal Neoplasms, Ureteral Neoplasms, business.industry, Stomach, Incidence (epidemiology), Cancer, Neoplasms, Second Primary, General Medicine, Middle Aged, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, Endometrial Neoplasms, medicine.anatomical_structure, Oncology, Colonic Neoplasms, Female, business |
| الوصف: | We examined the occurrence of second primary extracolonic cancers in 1,170 patients with nonpolyposis colorectal cancer who underwent a resection between 1972 and 1994. Such cancers occurred more often in cases with hereditary nonpolyposis colorectal cancer (HNPCC) than in those without (11.1% vs. 3.6%, P=0.0286). Five HNPCC cases developed 6 cancers in the stomach, endometrium, ovary, and ureter. The mean interval between the first and second operation was 66 months (range: 18-153). These findings thus indicate the importance of targetted surveillance for any second primary cancers in the upper gastrointestinal, female genital, or upper urologic tract, especially in HNPCC patients. |
| تدمد: | 1791-2431 1021-335X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11bb597f5b08984347fc5814dbf9d1a3Test https://doi.org/10.3892/or.5.1.143Test |
| رقم الانضمام: | edsair.doi.dedup.....11bb597f5b08984347fc5814dbf9d1a3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17912431 1021335X |
|---|