دورية أكاديمية
A case of severe nephrotic syndrome caused by isolated CMV glomerulopathy with ganciclovir resistant UL 97 mutation
العنوان: | A case of severe nephrotic syndrome caused by isolated CMV glomerulopathy with ganciclovir resistant UL 97 mutation |
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المؤلفون: | Ramez R. Sunna, Rupinder Sodhi, Francis Arden Purvis, Rosemary Ouseph, David S. Brink, Bahar Bastani |
المصدر: | Journal of Nephropathology, Vol 8, Iss 4, Pp e41-e41 (2019) |
بيانات النشر: | Society of Diabetic Nephropathy Prevention |
سنة النشر: | 2019 |
المجموعة: | Directory of Open Access Journals: DOAJ Articles |
مصطلحات موضوعية: | cmv glomerulopathy, cmv viremia, kidney transplant, ul 97 mutation, nephrotic syndrome, proteinuria, Pathology, RB1-214, Internal medicine, RC31-1245, Other systems of medicine, RZ201-999 |
الوصف: | Introduction: While many cases of cytomegalovirus (CMV) nephropathy have been reported in the literature, isolated CMV glomerulopathy is considered a rare finding. Case Presentation: We report the case of a CMV-negative recipient of kidney allograft from a CMVpositive donor (D+/R-), the recipient subsequently developed severe nephrotic syndrome secondary to biopsy-proven isolated CMV glomerulopathy. Conclusion: The patient developed CMV viremia with ganciclovir resistant UL97 mutation. His treatment course was resistant to recommended dose of intravenous ganciclovir, so therapy was changed to foscarnet with resolution of his viremia and reduction in proteinuria. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
تدمد: | 2251-8363 2251-8819 |
العلاقة: | https://nephropathol.com/PDF/jnp-8-41.pdfTest; https://doaj.org/toc/2251-8363Test; https://doaj.org/toc/2251-8819Test; https://doaj.org/article/b3d51cc893664208bb4b7615ad03a1bcTest |
DOI: | 10.15171/jnp.2019.41 |
الإتاحة: | https://doi.org/10.15171/jnp.2019.41Test https://doaj.org/article/b3d51cc893664208bb4b7615ad03a1bcTest |
رقم الانضمام: | edsbas.6A8360E9 |
قاعدة البيانات: | BASE |
تدمد: | 22518363 22518819 |
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DOI: | 10.15171/jnp.2019.41 |