Choleretic and antispasmodic effects of Lippia integrifolia aqueous extract
| العنوان: | Choleretic and antispasmodic effects of Lippia integrifolia aqueous extract |
|---|---|
| المؤلفون: | Cristina Vescina, Liliana Muschietti, Flavia Redko, Cristina Acevedo, Virginia Martino, Susana Gorzalczany, Valeria P. Sülsen |
| المصدر: | Revista Brasileira de Farmacognosia v.18 n.1 2008 Revista Brasileira de Farmacognosia Sociedade Brasileira de Farmacognosia (SBFgnosia) instacron:SBFGNOSIA Revista Brasileira de Farmacognosia, Vol 18, Iss 1, Pp 16-20 Revista Brasileira de Farmacognosia, Volume: 18, Issue: 1, Pages: 16-20, Published: MAR 2008 |
| بيانات النشر: | Sociedade Brasileira de Farmacognosia, 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | Choleretic, medicine.drug_class, lcsh:RS1-441, lcsh:Pharmacy and materia medica, chemistry.chemical_compound, Chlorogenic acid, Verbenaceae, medicine, General Pharmacology, Toxicology and Pharmaceutics, Aqueous extract, Traditional medicine, biology, Bile acid, efeito colerético, Lippia integrifolia, choleretic effect, antispasmodic effect, biology.organism_classification, chemistry, Biochemistry, efeito antiespasmódico, Antispasmodic, Acetylcholine, medicine.drug |
| الوصف: | The aqueous extract of the aerial parts of Lippia integrifolia has been assayed for its choleretic and antispasmodic effects. Doses of 250, 500 and 750 mg/kg administered orally in rats significantly increased the bile flow and the bile acid output. The extract also showed a significant reduction of the contractions induced by acetylcholine, CaCl2 and KCl on isolated rat jejunum. The total caffeoyl quinic acids derivatives content, expressed as chlorogenic acid was 0.10% w/v by spectrophotometric determination. O extrato aquoso das partes aéreas de Lippia integrifolia foi ensaiado quanto aos seus efeitos colerético e antiespasmódico. Doses de 250, 500 e 750 mg/kg administradas oralmente em ratos aumentaram significativamente o fluxo biliar e a saída de ácidos biliares. O extrato também exibiu uma significativa redução das contrações induzidas por acetilcolina, CaCl2 e KCl em jejuno isolado de rato. O conteúdo total de derivados dos ácidos cafeoilquínicos, expressado como ácido clorogênico foi de 0.10% w/v através de determinação espectrofotométrica. |
| وصف الملف: | text/html |
| اللغة: | English |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8ee1f29545fd37c8fa71b05766c98aTest http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000100005Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....0b8ee1f29545fd37c8fa71b05766c98a |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |