دورية أكاديمية
Heart Transplantation for Peripartum Cardiomyopathy: A Single-Center Experience
| العنوان: | Heart Transplantation for Peripartum Cardiomyopathy: A Single-Center Experience |
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| المؤلفون: | Nadia Bouabdallaoui, Pierre Demondion, Sylvestre Maréchaux, Shaida Varnous, Guillaume Lebreton, Frédéric Mouquet, Pascal Leprince |
| المصدر: | Arquivos Brasileiros de Cardiologia, Iss 0 (2018) |
| بيانات النشر: | Sociedade Brasileira de Cardiologia (SBC), 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: | Insuficiência Cardíaca, Cardiomiopatias / mortalidade, Período Periparto, Transplante de Coração, Rejeição de Enxerto / mortalidade, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Abstract Background: Peripartum cardiomyopathy is an idiopathic disorder defined by the occurrence of acute heart failure during late pregnancy or post-partum period in the absence of any other definable cause. Its clinical course is variable and severe cases might require heart transplantation. Objective: To investigate long-term outcomes after heart transplantation (HT) for peripartum cardiomyopathy (PPCM). Methods: Out of a single-center series of 1938 HT, 14 HT were performed for PPCM. We evaluated clinical characteristics, transplant-related complications, and long-term outcomes, in comparison with 28 sex-matched controls. Primary endpoint was death from any cause; secondary endpoints were transplant-related complications (rejection, infection, cardiac allograft vasculopathy). A value of p < 0.05 was considered of statistical significance. Results: PPCM patients and matched controls were comparable for most variables (all p values > 0.05), except for a higher use of inotropes at the time of HT in PPCM group (p = 0.03). During a median follow-up of 7.7 years, 16 patients died, 3 (21.5%) in PPCM group and 13 (46.5%) in control group. Mortality was significantly lower in PPCM group (p = 0.03). No significant difference was found in terms of transplant-related complications (p > 0.05). Conclusions: Long-term outcomes following HT for PPCM are favorable. Heart transplantation is a valuable option for PPCM patients who did not recover significantly under medical treatment. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Portuguese |
| تدمد: | 1678-4170 |
| العلاقة: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018005002103&lng=en&tlng=enTest; https://doaj.org/toc/1678-4170Test |
| DOI: | 10.5935/abc.20180014 |
| الوصول الحر: | https://doaj.org/article/a6428bf46d534261927dfd243c066f5eTest |
| رقم الانضمام: | edsdoj.6428bf46d534261927dfd243c066f5e |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16784170 |
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| DOI: | 10.5935/abc.20180014 |