Evolutive Study of Rheumatic Carditis Cases Treated with Corticosteroids in a Public Hospital
| العنوان: | Evolutive Study of Rheumatic Carditis Cases Treated with Corticosteroids in a Public Hospital |
|---|---|
| المؤلفون: | Cristina Ortiz Sobrinho Valete, Fernanda Maria Correia Ferreira Lemos, Gesmar Volga Haddad Herdy, Maria Eulália Thebit Pfeiffer |
| المصدر: | International Journal of Cardiovascular Sciences v.31 n.6 2018 International Journal of Cardiovascular Sciences Sociedade Brasileira de Cardiologia (SBC) instacron:SBC International Journal of Cardiovascular Sciences, Issue: ahead, Published: 23 AUG 2018 |
| بيانات النشر: | Sociedade Brasileira de Cardiologia, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Pediatrics, medicine.medical_specialty, Myocarditis/physiopathology, business.industry, Rheumatic carditis, Carditis, Mitral Valve Insufficiency, Retrospective cohort study, Secondary prophylaxis, Myocarditis/complications, medicine.disease, Penicilin G Benzathine, Corticosteroid therapy, Adrenal Cortex Hormones, medicine, Rheumatic fever, In patient, Observational study, Rheumatic Fever, business |
| الوصف: | Background: Rheumatic carditis is a challenge for treatment and secondary prophylaxis, due to severe valve sequelae. Objective: To evaluate the cases of rheumatic carditis in patients under 18 years old treated with corticosteroids. Methods: An observational, longitudinal and retrospective study was carried out on the profile of patients, in the period of 2000-2015. We selected those who received corticosteroid therapy at immunosuppressive doses, for the treatment of carditis and were aged 5 to 18 years. Data were extracted from medical records. Calculations of: averages, standard deviations, medians and interquartile ranges, ratios and 95% confidence intervals were obtained. Chi-square and Wilcoxon tests were applied for comparisons. The level of significance was 5%. Results: Of the 93 cases, 93.53% developed moderate or severe carditis. Mitral regurgitation was detected in 100% of the sample. Pulse therapy was administered in 11.83%. Surgery was performed in 23.69% of patients: mitral, aortic and/or tricuspid valve repair or replacement. The evolution of the cases was favorable in 70.96%. There was a good response among those who received only clinical treatment and those who belonged to the surgical group. The comparison of the initial and posterior valve lesions to the corticoid use was statistically significant (p < 0.001). A difference between the ejection fraction medians was observed (p = 0.048). Hospitalization was required twice or more for 45.16% of the patients. The mortality rate was 5.38%. Conclusions: The patients showed significant clinical improvement. The treatment was effective, reducing trivalvular impairment. |
| وصف الملف: | text/html |
| اللغة: | English |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe5617a8aaf23e564739c572ef73a00Test http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472018000600578Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....6fe5617a8aaf23e564739c572ef73a00 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |