دورية أكاديمية

The role of ultrasound and ultrasound-guided fine needle aspiration biopsy of lymph nodes in patients with skin tumours.

التفاصيل البيبلوغرافية
العنوان: The role of ultrasound and ultrasound-guided fine needle aspiration biopsy of lymph nodes in patients with skin tumours.
المؤلفون: Solivetti, Francesco Maria, Elia, Fulvia, Santaguida, Maria Giulia, Guerrisi, Antonino, Visca, Paolo, Cercato, Maria Cecilia, Di Carlo, Aldo
المصدر: Radiology & Oncology; Mar2014, Vol. 48 Issue 1, p29-34, 6p
مصطلحات موضوعية: METASTASIS, NEEDLE biopsy, CYTOLOGICAL techniques, PATIENT aftercare, LONGITUDINAL method, LYMPH nodes, SKIN tumors, ULTRASONIC imaging, EVALUATION research, PREDICTIVE tests, DICOM (Computer network protocol), DATA analysis software, DESCRIPTIVE statistics, DIAGNOSIS
مستخلص: Background. The primary aim of this study was to evaluate the diagnostic accuracy of ultrasound (US) in the study of superficial lymph nodes during the follow-up of patients surgically treated for skin tumours. The secondary objective was to compare positive cytological results with histological reports. Patients and methods. From 2004 to 2011, 480 patients (male/female: 285/195; median age 57 years; prevalent skin tumour: melanoma) underwent US-guided fine-needle aspiration biopsy (FNAB) of suspicious recurrent lymph nodes. An expert radiologist first performed US testing of the lymph nodes, expressing either a negative or positive outcome of the test. Subsequently, US-guided FNAB was performed. FNAB positive patients were subjected to lymphadenectomy; the patients who tested negative underwent the follow-up. Results. The size of lymph nodes was ≤ 2 cm in 90% of cases. Out of the 336 (70%) US 'positive' patients, 231 (68.8%) were FNAB positives. Out of the 144 (30%) US 'negatives', 132 (91.7%) were FNAB negatives. The sensitivity and specificity of the US were 95% and 55.7%, respectively; the negative predictive value was 91.7% and the positive predictive value was 68.8%. Definitive histological results confirmed FNAB positivity in 97.5% of lymphadenectomies. Conclusions. US is a sensitive method in the evaluation of superficial lymph nodes during the follow-up of patients with skin tumours. High positive predictive value of cytology was confirmed. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:13182099
DOI:10.2478/raon-2013-0084