التفاصيل البيبلوغرافية
| العنوان: |
The application of magnetic resonance spectroscopy to investigate the effect of a commercial energy drink |
| المؤلفون: |
Burrows, Tracy L., Pursey, Kirrilly M., Stanwell, Peter |
| المساهمون: |
The University of Newcastle. Faculty of Health & Medicine, School of Health Sciences |
| بيانات النشر: |
Sciencedomain International |
| سنة النشر: |
2015 |
| المجموعة: |
NOVA: The University of Newcastle Research Online (Australia) |
| مصطلحات موضوعية: |
energy drink, magnetic resonance spectroscopy, MRS |
| الوصف: |
Aims: Proton magnetic resonance spectroscopy (MRS) is an imaging technique that provides non-invasive, in-vivo measurement of brain biochemistry. The objective of this study was to explore the effects of a commercial energy drink (ED) on brain metabolites in adult males using MRS. Methods: Ten males (18 to 30 years), of mean body mass index 23.8±2.2 kg/m² [range 21.4-27.8 kg/m²] were recruited and randomized to either the intervention group (n=5) or control group (n=5). The intervention group were asked to consume two 250ml cans of Red Bull and the control group consumed no drink. One dimensional MRS on a 1.5T Achieva MRI scanner was obtained of bi-occipital gray matter. Subjects were placed in the scanner and a spectrum acquired every 5.75 minutes for 60 minutes. Linear mixed models were generated to determine the main effects due to differences between groups and times and the interaction. Results: There was a significant group by time effect for N-acetylaspartate (NAA) (P= .02, d= 0.7) and a statistical trend for macromolecule 20 (MM20) (P= .06 d= 0.1) with the control group having higher concentrations than that of the intervention. Mean differences from baseline to 45 minutes for NAA in the intervention group were -0.8 mM (-12%) compared with 0.15 mM (<1%) for control and for MM20 -0.12 mM (<1%) in the intervention group compared with 0.03 mM (<1%) for control. Conclusions: Consumption of two cans of ED was found to produce few changes in brain metabolites with moderate effect sizes. Changes detected in this study demonstrate the sensitivity of the MRS method to explore nutrition related variables with 1.5T clinical MRI unit. The study provides some insight into an understudied, topical area of research. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| تدمد: |
2347-5641 |
| العلاقة: |
European Journal of Nutrition & Food Safety Vol. 5, Issue 1, p. 75-87; http://hdl.handle.net/1959.13/1333690Test; uon:27129 |
| الإتاحة: |
http://hdl.handle.net/1959.13/1333690Test |
| حقوق: |
© 2015 Burrows et al.; This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0Test), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| رقم الانضمام: |
edsbas.1F97056A |
| قاعدة البيانات: |
BASE |
