Quality Control for RNA-Seq (QuaCRS): An Integrated Quality Control Pipeline
| العنوان: | Quality Control for RNA-Seq (QuaCRS): An Integrated Quality Control Pipeline |
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| المؤلفون: | Nima E. Mokaram, Karl Kroll, Cameron L. Stump, Alexander R. Pelletier, Paige A. Stump, Maximillian Westphal, David Frankhouser, Ralf Bundschuh, Pearlly S. Yan, James S. Blachly |
| المصدر: | Cancer Informatics, Vol 2014, Iss Suppl. 3, Pp 7-14 (2014) Cancer Informatics, Vol 13s3 (2014) Cancer Informatics |
| بيانات النشر: | SAGE Publishing, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | FastQC, Cancer Research, Source code, Computer science, media_common.quotation_subject, Sample (statistics), computer.software_genre, lcsh:RC254-282, RNA-SeQC, sort, Quality (business), quality control, database, Original Research, media_common, Database, business.industry, Usability, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Data science, Pipeline (software), Oncology, RSeQC, Data quality, RNA-seq, User interface, business, computer |
| الوصف: | QuaCRS ( Quality Control for RNA- Seq) is an integrated, simplified quality control (QC) system for RNA-seq data that allows easy execution of several open-source QC tools, aggregation of their output, and the ability to quickly identify quality issues by performing meta-analyses on QC metrics across large numbers of samples in different studies. It comprises two main sections. First is the QC Pack wrapper, which executes three QC tools: FastQC, RNA-SeQC, and selected functions from RSeQC. Combining these three tools into one wrapper provides increased ease of use and provides a much more complete view of sample data quality than any individual tool. Second is the QC database, which displays the resulting metrics in a user-friendly web interface. It was designed to allow users with less computational experience to easily generate and view QC information for their data, to investigate individual samples and aggregate reports of sample groups, and to sort and search samples based on quality. The structure of the QuaCRS database is designed to enable expansion with additional tools and metrics in the future. The source code for not-for-profit use and a fully functional sample user interface with mock data are available at http://bioserv.mps.ohio-state.edu/QuaCRSTest/ . |
| اللغة: | English |
| تدمد: | 1176-9351 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7244fb45790162578769a36a5c065c69Test http://www.la-press.com/quality-control-for-rna-seq-quacrs-an-integrated-quality-control-pipel-article-a4453Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....7244fb45790162578769a36a5c065c69 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 11769351 |
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