دورية أكاديمية
Expert recommendations on the management of patients with metastatic castration-resistant prostate cancer who progress after CHAARTED or LATITUDE
العنوان: | Expert recommendations on the management of patients with metastatic castration-resistant prostate cancer who progress after CHAARTED or LATITUDE |
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المؤلفون: | Puente, Javier, Anido, Urbano, Angel Climent, Miguel, Gonzalez-Billalabeitia, Enrique, Lainez, Nuria, Lambea, Julio, Pablo Maroto, Jose, Jose Mendez-Vidal, Maria, Montesa, Alvaro, Rodriguez, Angel, Zambrana, Curro, Gonzalez-del-Alba, Aranzazu |
المساهمون: | Gonzalez-del-Alba, Aranzazu Hosp Univ Puerta Hierro Majadahonda, Med Ongol Dept, Calle Joaquin Rodrigo 2, Madrid 28222, Spain, Puente, Javier Hosp Clin San Carlos, CIBERONC, Inst Invest Sanitaria Hosp Clin San Carlos IdISSC, Med Oncol Dept, Madrid, Spain, Anido, Urbano Complejo Hosp Univ Santiago, Oncol Dept, Santiago De Compostela, Spain, Angel Climent, Miguel IVO, Med Oncol Dept, Valencia, Spain, Gonzalez-Billalabeitia, Enrique Univ Murcia, IMIB, Hosp Univ Morales Meseguer, Hematol & Med Oncol Dept, Murcia, Spain, Gonzalez-Billalabeitia, Enrique Univ Catolica San Antonio Murcia UCAM, Murcia, Spain, Lainez, Nuria Complejo Hosp Navarra, Med Oncol Dept, Pamplona, Spain, Lambea, Julio Hosp Clin Univ Lozano Blesa, Med Oncol Dept, Zaragoza, Spain, Pablo Maroto, Jose Hosp Santa Creu & Sant Pau, Med Oncol Dept, Barcelona, Spain, Jose Mendez-Vidal, Maria Hosp Univ Reina Sofia, Med Oncol Dept, Cordoba, Spain, Montesa, Alvaro Hosp Reg Malaga, Med Oncol Dept, Malaga, Spain, Rodriguez, Angel Hosp Leon, Med Oncol Dept, Leon, Spain, Zambrana, Curro Hosp Univ Infanta Sofia, Med Oncol Dept, San Sebastian De Reyes, Spain, Sanofi |
بيانات النشر: | Sage publications ltd |
سنة النشر: | 2020 |
المجموعة: | Sistema Sanitario Público de Andalucía (SSPA): Repositorio |
مصطلحات موضوعية: | abiraterone acetate, androgen-deprivation therapy, chemotherapy, enzalutamide, metastatic castration-resistant prostate cancer, radium-223, Androgen deprivation therapy, Increased survival, Docetaxel, Men, Cabazitaxel, 1st-line, Upfront |
الوصف: | Objective:Our aim was to provide practical recommendations on the management of patients with metastatic castration-resistant prostate cancer (mCRPC) who have progressed after docetaxel plus androgen-deprivation therapy (ADT) or abiraterone plus ADT.Methods:Systematic literature review (SLR), nominal group meeting, and Delphi process. A panel of 12 experts was established who defined the scope, users, and sections of the document. We performed an SLR in order to assess the efficacy and safety of available drugs in patients with mCRPC. Abstracts from the American Society of Oncology and European Society for Medical Oncology meetings were also examined. The results were discussed during an expert meeting in which 14 recommendations were generated. The level of agreement with the recommendations was also tested by 13 additional experts following the Delphi process. Recommendations were voted by means of scores ranging from 0 (total disagreement) to 10 (total agreement). We defined agreement when at least 70% of the experts voted > 7. Next, we assigned a level of evidence and grade to the recommendation using the Oxford Centre for Evidence-based Medicine Levels of Evidence, following which the final document was drafted.Results:The literature search did not find any articles meeting the inclusion criteria. Finally, 13 out of 14 recommendations were accepted after two Delphi rounds (two were modified after the first round). They pertain to general and individual case-based treatment recommendations.Conclusions:In mCRPC patients who have progressed after docetaxel or abiraterone plus ADT in the metastatic hormone-sensitive prostate cancer setting, these recommendations may support treatment decision-making, due to the lack of evidence or other globally accepted sequencing algorithms. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
ردمك: | 978-5-388-73800-4 5-388-73800-0 |
تدمد: | 1758-8340 1758-8359 |
العلاقة: | http://hdl.handle.net/10668/19103Test; https://doi.org/10.1177/1758835920920067Test; 538873800001 |
DOI: | 10.1177/1758835920920067 |
الإتاحة: | https://doi.org/10.1177/1758835920920067Test http://hdl.handle.net/10668/19103Test |
حقوق: | Attribution-NonCommercial 4.0 International ; http://creativecommons.org/licenses/by-nc/4.0Test/ ; open access |
رقم الانضمام: | edsbas.29ACAA35 |
قاعدة البيانات: | BASE |
ردمك: | 9785388738004 5388738000 |
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تدمد: | 17588340 17588359 |
DOI: | 10.1177/1758835920920067 |