التفاصيل البيبلوغرافية
| العنوان: |
Longitudinal changes in cerebral blood flow velocities in different clinical courses of migraine. |
| المؤلفون: |
Mi Ji Lee1, Min Kyung Chu2, Hanna Choi3, Hyun Ah Choi1, Chungbin Lee1, Chin-Sang Chung1 cspaul@naver.com, Lee, Mi Ji4 (AUTHOR), Chu, Min Kyung5 (AUTHOR), Choi, Hanna6 (AUTHOR), Choi, Hyun Ah4 (AUTHOR), Lee, Chungbin4 (AUTHOR), Chung, Chin-Sang4 (AUTHOR) |
| المصدر: |
Cephalalgia. Sep2017, Vol. 37 Issue 10, p927-937. 11p. |
| مصطلحات موضوعية: |
*MIGRAINE, *CEREBRAL circulation, *HEMODYNAMICS, *TRANSCRANIAL Doppler ultrasonography, *NEUROPHYSIOLOGY, *HEADACHE treatment, *PATIENTS |
| مستخلص: |
Objective To assess longitudinal changes in cerebral blood flow velocities (ΔCBFVs) according to the clinical course of migraine. Methods We retrospectively included migraine patients with two or more attacks per month at baseline who were followed up within 2 years with transcranial Doppler in a tertiary headache clinic. ΔCBFVs were analyzed in relation to clinical courses, defined as remission (0-1 headache days/month), persistence (2-14/month), or progression (≥15/month) in episodic migraine (EM), and conversion to EM (<15/month) and persistence (≥15/month) in chronic migraine (CM). Results A total of 166 patients (90 EM and 76 CM) were included. In EM, the remission group ( n = 30) showed a decrease in CBFV in the middle cerebral artery (MCA) and the basilar artery (BA). The progression group ( n = 10) showed increasing CBFVs in the bilateral MCAs. Patients with the persistence course ( n = 50) showed generally unchanged CBFVs. In CM, ΔCBFVs decreased in the BA and increased in the posterior cerebral artery (PCA) after conversion to EM ( n = 61), whereas they remained unchanged in the persistence group ( n = 15). In all patients, % change in headache days was positively correlated with the %ΔCBFVs of the bilateral MCAs and the BA. Conclusions CBFV changes are associated with the different clinical courses of migraine. The association is more prominent in EM than CM. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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